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yolk sac tumor of central nervous system - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

yolk sac tumor of central nervous system

MONDO:0016739

Also known as:CNS yolk Sac tumorCNS yolk Sac tumourcentral nervous system yolk Sac tumor

Overview

A malignant germ cell tumor of the central nervous system composed of primitive-appearing epithelial cells - putatively representing yolk sac endoderm - set in a loose, variably cellular, and often conspicuously myxoid matrix, resembling extra-embryonic mesoblast. Eosinophilic hyaline globules immunoreactive for AFP are a diagnostic feature. (WHO)

Diagnosis

Biomarker and diagnostic research for yolk sac tumor of central nervous system has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for yolk sac tumor of central nervous system.

15 publications have been identified in PubMed for yolk sac tumor of central nervous system. Research spans Case Report / Case Series (50%), Basic Science / Preclinical (25%), and Review / Meta-Analysis (17%).

Research Type	Count	% of Total
Patient case studies	6	50%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:31 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:252006

GARD

Genetic and Rare Diseases Info Center

GARD:20733

Questions for Your Care Team

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yolk sac tumor of central nervous system

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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