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A medulloblastoma SHH activated that is characterized as a molecular subtype by activation of the sonic hedgehog (SHH) pathway and the presence of TP53 mutations.
Biomarker and diagnostic research for medulloblastoma SHH activated and TP53 mutant has been reported in the published literature.
No clinical trials have been registered for medulloblastoma SHH activated and TP53 mutant.
8 publications have been identified in PubMed for medulloblastoma SHH activated and TP53 mutant. Research spans Case Report / Case Series (29%), Basic Science / Preclinical (29%), and Diagnostic / Biomarker (14%).
Comer C (2026). [PMID: 41923098](https://pubmed.ncbi.nlm.nih.gov/41923098/). *Biol Direct*. [Basic Science / Preclinical]
Moreno DA (2025). [PMID: 40880425](https://pubmed.ncbi.nlm.nih.gov/40880425/). *Animal Model Exp Med*. [Case Report / Case Series]
Adhvaryu VV (2025). [PMID: 40302434](https://pubmed.ncbi.nlm.nih.gov/40302434/). *Int J Surg Pathol*. [Epidemiology / Natural History]
Zheng H (2025). [PMID: 40388014](https://pubmed.ncbi.nlm.nih.gov/40388014/). *Invest New Drugs*. [Case Report / Case Series]
DeCarlo A (2025). [PMID: 40562042](https://pubmed.ncbi.nlm.nih.gov/40562042/). *Cell Rep Med*. [Gene Therapy / Novel Therapeutics]
Data assembled from 2 of 12 sources · Last updated Sep 20, 2026, 8:42 AM UTC
Salimian M (2024). [PMID: 38078513](https://pubmed.ncbi.nlm.nih.gov/38078513/). *Cytopathology*. [Diagnostic / Biomarker]
Motahari Z (2024). [PMID: 39436961](https://pubmed.ncbi.nlm.nih.gov/39436961/). *PLoS One*. [Basic Science / Preclinical]