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medulloblastoma SHH activated and TP53 wild-type - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

medulloblastoma SHH activated and TP53 wild-type

MONDO:0956965

Overview

A medulloblastoma SHH activated that is characterized as a molecular subtype by activation of the sonic hedgehog (SHH) pathway and the absence of TP53 mutations.

ResearchLimited published research (5 articles)

Diagnosis

Biomarker and diagnostic research for medulloblastoma SHH activated and TP53 wild-type has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for medulloblastoma SHH activated and TP53 wild-type.

5 publications have been identified in PubMed for medulloblastoma SHH activated and TP53 wild-type. Research spans Basic Science / Preclinical (40%), Diagnostic / Biomarker (20%), and Review / Meta-Analysis (20%).

Recent Publications

Comer C (2026). [PMID: 41923098](https://pubmed.ncbi.nlm.nih.gov/41923098/). *Biol Direct*. [Basic Science / Preclinical]
Ruggiero A (2026). [PMID: 41899451](https://pubmed.ncbi.nlm.nih.gov/41899451/). *Curr Issues Mol Biol*. [Review / Meta-Analysis]
Ranade M (2025). [PMID: 40528003](https://pubmed.ncbi.nlm.nih.gov/40528003/). *Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery*. [Diagnostic / Biomarker]
Moreno DA (2025). [PMID: 40880425](https://pubmed.ncbi.nlm.nih.gov/40880425/). *Animal models and experimental medicine*. [Basic Science / Preclinical]
Cabezas-Camarero S (2024). [PMID: 38438322](https://pubmed.ncbi.nlm.nih.gov/38438322/). *The oncologist*. [Gene Therapy / Novel Therapeutics]

Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 3:02 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

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medulloblastoma SHH activated and TP53 wild-type

Overview

Diagnosis

Research Landscape

Recent Publications

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team