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Type III mixed cryoglobulinemia, a relatively rare clinico-serological subtype of mixed cryoglobulinemia (MC), is an immune complex disorder characterized by purpura, weakness and arthralgia and defined immunochemically by cryoglobulins containing both polyclonal IgGs and polyclonal IgMs.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for mixed cryoglobulinemia type III.
13 publications have been identified in PubMed for mixed cryoglobulinemia type III. Research spans Case Report / Case Series (58%), Review / Meta-Analysis (17%), and Epidemiology / Natural History (17%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 7 | 58% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 10:42 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries
2 |
17% |
Disease patterns and progression | 2 | 17% |
Other research | 1 | 8% |
German A (2026). [PMID: 41505689](https://pubmed.ncbi.nlm.nih.gov/41505689/). *Neurology*. [Case Report / Case Series]
Zignego AL (2026). [PMID: 41298332](https://pubmed.ncbi.nlm.nih.gov/41298332/). *Journal of internal medicine*. [Review / Meta-Analysis]
Tao J (2026). [PMID: 41853328](https://pubmed.ncbi.nlm.nih.gov/41853328/). *Kidney medicine*. [Case Report / Case Series]
Thivacaren S (2025). [PMID: 41245923](https://pubmed.ncbi.nlm.nih.gov/41245923/). *Cureus*. [Epidemiology / Natural History]
Elthes BZ (2025). [PMID: 40210820](https://pubmed.ncbi.nlm.nih.gov/40210820/). *Digestive diseases and sciences*. [Case Report / Case Series]
Villa A (2025). [PMID: 40566113](https://pubmed.ncbi.nlm.nih.gov/40566113/). *Journal of clinical medicine*. [Review / Meta-Analysis]
Duggal S (2025). [PMID: 40176858](https://pubmed.ncbi.nlm.nih.gov/40176858/). *EJHaem*. [Case Report / Case Series]
Reyes-Báez O (2025). [PMID: 40978947](https://pubmed.ncbi.nlm.nih.gov/40978947/). *Cureus*. [Case Report / Case Series]
Xu Q (2024). [PMID: 38730122](https://pubmed.ncbi.nlm.nih.gov/38730122/). *Clinical rheumatology*. [Case Report / Case Series]
Reinberg C (2024). [PMID: 39076993](https://pubmed.ncbi.nlm.nih.gov/39076993/). *Frontiers in immunology*. [Other]
AI-curated news mentioning mixed cryoglobulinemia type III
Updated Mar 7, 2026
A recent study published in PubMed highlights sustained remission in patients with cryoglobulinemia type II following B-cell-directed therapy. This research may inform future treatment strategies for this rare disease.