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83 clinical trials registered, 46 recruiting. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE4, 8 PHASE3, 24 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05280509](https://clinicaltrials.gov/study/NCT05280509) |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 3:00 PM UTC
Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib |
PHASE1 |
Telios Pharma, Inc. |
RECRUITING |
[NCT05123365](https://clinicaltrials.gov/study/NCT05123365) | An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms | PHASE1 | University of California, Irvine | RECRUITING |
[NCT06164561](https://clinicaltrials.gov/study/NCT06164561) | 18F-FAPI PET/MRI Imaging in Myelofibrosis: a Prospective Observational Study. | — | First Affiliated Hospital of Zhejiang University | RECRUITING |
[NCT06378437](https://clinicaltrials.gov/study/NCT06378437) | A Study of GLB-001 in Patients With Myeloid Malignancies | PHASE1 | Hangzhou GluBio Pharmaceutical Co., Ltd. | RECRUITING |
[NCT03452774](https://clinicaltrials.gov/study/NCT03452774) | SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry | — | Massive Bio, Inc. | RECRUITING |
2 publications have been identified in PubMed for myelofibrosis with myeloid metaplasia. Research spans Review / Meta-Analysis (50%) and Case Report / Case Series (50%).
Thiele J (2025). [PMID: 40038244](https://pubmed.ncbi.nlm.nih.gov/40038244/). *Blood Cancer J*. [Review / Meta-Analysis]
Al-Maghrabi H (2025). [PMID: 40421095](https://pubmed.ncbi.nlm.nih.gov/40421095/). *Front Oncol*. [Case Report / Case Series]
AI-curated news mentioning myelofibrosis with myeloid metaplasia
Updated Jan 23, 2026
The MPN PROGRESSion Registry is launched to track symptoms, treatments, and disease progression in individuals with myeloproliferative neoplasms (MPNs). This observational study aims to enhance understanding of conditions like Polycythemia Vera and Essential Thrombocythemia.