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A self-limited skin rash that appears in the neonatal period and usually resolves in four to six months after birth. It is caused by placental transfer of maternal autoantibodies, usually anti-Ro antibody. In a minority of cases, it is associated with congenital heart block, hepatitis, or thrombocytopenia. The mothers of the affected babies may be asymptomatic or suffer from systemic lupus erythematosus, Sjogren's syndrome, or rheumatoid arthritis.
1 clinical trial registered. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.
72 publications have been identified in PubMed for neonatal lupus erythematosus. Kisho has analyzed 56 by research type. Research spans Case Report / Case Series (48%), Review / Meta-Analysis (29%), and Epidemiology / Natural History (18%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 27 |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 9:40 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries | 16 | 29% |
Disease patterns and progression | 10 | 18% |
Other research | 2 | 4% |
Laboratory research | 1 | 2% |
Adegboye C (2026). [PMID: 41672754](https://pubmed.ncbi.nlm.nih.gov/41672754/). *Arch Dis Child Fetal Neonatal Ed*. [Review / Meta-Analysis]
Guedes S (2026). [PMID: 41694992](https://pubmed.ncbi.nlm.nih.gov/41694992/). *Cureus*. [Case Report / Case Series]
Cho A (2026). [PMID: 40986070](https://pubmed.ncbi.nlm.nih.gov/40986070/). *Dermatologie (Heidelb)*. [Case Report / Case Series]
Zhou SY (2026). [PMID: 41940214](https://pubmed.ncbi.nlm.nih.gov/41940214/). *Obstet Med*. [Review / Meta-Analysis]
Menchaca-Aguayo H (2026). [PMID: 41802920](https://pubmed.ncbi.nlm.nih.gov/41802920/). *Pediatr Dermatol*. [Case Report / Case Series]
Kawuryan DL (2026). [PMID: 41742631](https://pubmed.ncbi.nlm.nih.gov/41742631/). *Am J Case Rep*. [Case Report / Case Series]
Carlucci PM (2026). [PMID: 41111019](https://pubmed.ncbi.nlm.nih.gov/41111019/). *Ann Rheum Dis*. [Case Report / Case Series]
Sun W (2026). [PMID: 41727492](https://pubmed.ncbi.nlm.nih.gov/41727492/). *Front Immunol*. [Epidemiology / Natural History]
Zhang X (2026). [PMID: 41178668](https://pubmed.ncbi.nlm.nih.gov/41178668/). *Br J Dermatol*. [Review / Meta-Analysis]
Manolis AA (2026). [PMID: 40207823](https://pubmed.ncbi.nlm.nih.gov/40207823/). *Curr Vasc Pharmacol*. [Review / Meta-Analysis]
AI-curated news mentioning neonatal lupus erythematosus
Updated Sep 1, 2026
Recent research highlights the connection between neonatal lupus and congenital heart block, providing insights into the underlying mechanisms. This study may enhance understanding and management of these conditions.