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nevus of Ota - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

nevus of Ota

MONDO:0016984

Also known as:Nevus fusculoceruleus ophthalmomaxillarisOta's Nevusoculocutaneous melanocytic Nevus

Overview

Nevus of Ota is an oculodermal melanocytosis more commonly found in Asian and African populations, usually present at birth and characterized by a usually unilateral, bluish gray, patchy, speckled pigmentation (that may progressively enlarge and darken) affecting the skin of the face along the distribution of the ophthalmic and maxillary divisions of the trigeminal nerve (periorbital region, temple, forehead, malar area, nose). In 2/3 cases the ipsilateral sclera is affected. Nevus of Ota usually remains stable once adulthood is reached but an increased risk of glaucoma and uveal melanoma may be observed. Extracutaneous lesions may also occur in cornea, retina, tympanum, nasal mucosa, pharynx, palate. Nevus of Ota occurs as solitary conditions but seldom may occur together with the nevus of Ito or nevus spilus.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for nevus of Ota.

51 publications have been identified in PubMed for nevus of Ota. Research spans Case Report / Case Series (49%), Review / Meta-Analysis (18%), and Clinical Trial Publication (18%).

Research Type	Count	% of Total
Patient case studies	24	49%

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 8:02 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:263425

GARD

Genetic and Rare Diseases Info Center

GARD:20901

Questions for Your Care Team

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nevus of Ota

Overview

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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