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nodular lymphocyte predominant Hodgkin lymphoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

nodular lymphocyte predominant Hodgkin lymphoma

MONDO:0044778

Also known as:Hodgkin lymphoma nodular LP, NOSHodgkin lymphoma nodular lymphocyte predominant type, NOSNLPHL

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Overview

A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008)

Clinical Trials1 registered

Diagnosis

Biomarker and diagnostic research for nodular lymphocyte predominant Hodgkin lymphoma has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.

57 publications have been identified in PubMed for nodular lymphocyte predominant Hodgkin lymphoma. Research spans Case Report / Case Series (21%), Diagnostic / Biomarker (20%), and Review / Meta-Analysis (20%).

Research Type	Count	% of Total
Patient case studies	12	21%

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:11 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:86893

GARD

Genetic and Rare Diseases Info Center

GARD:19079

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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nodular lymphocyte predominant Hodgkin lymphoma

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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