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Orgasm-induced seizures is a rare neurologic disease characterized by complex partial seizures with or without secondary generalization, or idiopathic primarily generalized epilepsy, triggered by sexual orgasm. Seizures usually start immediately, shortly after or a few hours after the achievement of orgasm, last a few seconds or minutes, and are followed, in very rare cases, by intense migraine.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for orgasm-induced seizures.
1 publication has been identified in PubMed for orgasm-induced seizures. Research spans Case Report / Case Series (100%).
Yan J (2025). [PMID: 40761217](https://pubmed.ncbi.nlm.nih.gov/40761217/). *AME case reports*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 7:49 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center