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Reflex epilepsy refers to epilepsies where recurrent seizures are provoked by a clearly defined extrinsic (most commonly) or intrinsic triggering stimuli such as flashing lights (photosensitive epilepsy), startling noises (startle epilepsy), urinating (micturition induced seizures), exposure to hot-water (hot water epilepsy), eating, reading, and thinking, while being associated with an enduring abnormal predisposition to have such seizures (thereby meeting the conceptual definition of epilepsy).
Biomarker and diagnostic research for reflex epilepsy has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
2 clinical trials registered. Interventions under study include other interventions and medical devices. Pipeline includes 2 NA. Research is primarily sponsored by academic and government institutions.
144 publications have been identified in PubMed for reflex epilepsy. Research spans Basic Science / Preclinical (36%), Case Report / Case Series (28%), and Clinical Trial Publication (9%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 52 |
Data assembled from 4 of 12 sources · Last updated Oct 3, 2026, 10:25 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Patient case studies | 41 | 28% |
Clinical study results | 13 | 9% |
Disease patterns and progression | 13 | 9% |
Research summaries | 11 | 8% |
Testing and diagnosis research | 8 | 6% |
New treatment approaches | 6 | 4% |
Higgins J (2026). [PMID: 41718488](https://pubmed.ncbi.nlm.nih.gov/41718488/). *Epilepsia Open*. [Basic Science / Preclinical]
Figueroa AG (2026). [PMID: 41831475](https://pubmed.ncbi.nlm.nih.gov/41831475/). *The Lancet. Neurology*. [Basic Science / Preclinical]
Koepp MJ (2026). [PMID: 41459805](https://pubmed.ncbi.nlm.nih.gov/41459805/). *Annals of neurology*. [Gene Therapy / Novel Therapeutics]
Li Y (2026). [PMID: 41545509](https://pubmed.ncbi.nlm.nih.gov/41545509/). *Scientific reports*. [Diagnostic / Biomarker]
Yuste R (2026). [PMID: 41789717](https://pubmed.ncbi.nlm.nih.gov/41789717/). *Physiological reviews*. [Case Report / Case Series]
Wang HC (2026). [PMID: 41608561](https://pubmed.ncbi.nlm.nih.gov/41608561/). *Theranostics*. [Basic Science / Preclinical]
Fisher RS (2026). [PMID: 41283196](https://pubmed.ncbi.nlm.nih.gov/41283196/). *Epilepsia*. [Review / Meta-Analysis]
Gupta T (2026). [PMID: 41639510](https://pubmed.ncbi.nlm.nih.gov/41639510/). *Indian journal of pediatrics*. [Case Report / Case Series]
Asranna A (2026). [PMID: 41222148](https://pubmed.ncbi.nlm.nih.gov/41222148/). *Epileptic disorders : international epilepsy journal with videotape*. [Epidemiology / Natural History]
Finkelshtain S (2026). [PMID: 41235500](https://pubmed.ncbi.nlm.nih.gov/41235500/). *Epileptic disorders : international epilepsy journal with videotape*. [Case Report / Case Series]