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A rare bone disease characterized by avascular necrosis of the navicular bone in children. Patients present with sudden unexplained foot pain, inability to bear weight, and limping. Radiographic features include flattening, fragmentation, and patchy sclerosis of the navicular bone. Soft tissue swelling may be associated. The condition is most commonly unilateral and self-limiting. Boys are more often affected than girls.
Biomarker and diagnostic research for osteochondritis of tarsal/metatarsal bone has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for osteochondritis of tarsal/metatarsal bone.
18 publications have been identified in PubMed for osteochondritis of tarsal/metatarsal bone. Research spans Case Report / Case Series (33%), Other (17%), and Basic Science / Preclinical (17%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 6 | 33% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:35 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Other research
3 |
17% |
Laboratory research | 3 | 17% |
Research summaries | 2 | 11% |
Clinical study results | 2 | 11% |
Testing and diagnosis research | 1 | 6% |
Disease patterns and progression | 1 | 6% |
Liu J (2026). [PMID: 41674022](https://pubmed.ncbi.nlm.nih.gov/41674022/). *J Clin Ultrasound*. [Case Report / Case Series]
Zingel MM (2026). [PMID: 40719109](https://pubmed.ncbi.nlm.nih.gov/40719109/). *Vet Comp Orthop Traumatol*. [Clinical Trial Publication]
Trammell AP (2026). [PMID: 29939608](https://pubmed.ncbi.nlm.nih.gov/29939608/). *Unknown Journal*. [Other]
Bartoníček J (2026). [PMID: 41902913](https://pubmed.ncbi.nlm.nih.gov/41902913/). *Int Orthop*. [Other]
Wikstrom EA (2025). [PMID: 41473123](https://pubmed.ncbi.nlm.nih.gov/41473123/). *J Athl Train*. [Case Report / Case Series]
Riva MA (2025). [PMID: 41338216](https://pubmed.ncbi.nlm.nih.gov/41338216/). *Semin Musculoskelet Radiol*. [Other]
Holley KW (2025). [PMID: 40918866](https://pubmed.ncbi.nlm.nih.gov/40918866/). *Cureus*. [Case Report / Case Series]
Kühle J (2025). [PMID: 39856418](https://pubmed.ncbi.nlm.nih.gov/39856418/). *Arch Orthop Trauma Surg*. [Basic Science / Preclinical]
Chester A (2025). [PMID: 41325589](https://pubmed.ncbi.nlm.nih.gov/41325589/). *J Am Acad Orthop Surg Glob Res Rev*. [Case Report / Case Series]
Soy F (2025). [PMID: 40520757](https://pubmed.ncbi.nlm.nih.gov/40520757/). *J Orthop Case Rep*. [Case Report / Case Series]