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panner disease - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

panner disease

MONDO:0019969

Also known as:Osteochondrosis of the capital humerusaseptic necrosis of the capital humerus

Overview

Panner's disease is an osteochondrosis of the capitellum of the humerus, characterized by involvement of the dominant upper limb and onset before the age of 10 years. It results from lateral compression injuries of the elbow typically occurring in children practicing sports such as baseball and throw. It should be distinguished from osteochondritis dissecans of the capitellum, occurring later, in adolescents. Management is symptomatic and consists in reducing the activities of the affected elbow for a prolonged period of time. Prognosis is good.

ResearchLimited published research (8 articles)

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Abnormality of upper limb joint and Osteochondrosis; and common findings: Limited elbow extension, Joint swelling, Limited elbow movement, and Abnormal humerus morphology and others. 11 total HPO annotations.

Organ System	Phenotype Count	Example Features
Bones and joints	4	Abnormality of upper limb joint, Osteochondrosis, Joint swelling

Diagnosis

Biomarker and diagnostic research for panner disease has been reported in the published literature.

Prognosis

Phenotype severity distribution: 2 very common features, 5 common features.

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for panner disease.

8 publications have been identified in PubMed for panner disease. Research spans Other (25%), Review / Meta-Analysis (25%), and Basic Science / Preclinical (25%).

Recent Publications

Álvez MB (2025). [PMID: 41066540](https://pubmed.ncbi.nlm.nih.gov/41066540/). *Science*. [Basic Science / Preclinical]
Banerjee R (2025). [PMID: 39672991](https://pubmed.ncbi.nlm.nih.gov/39672991/). *Med Biol Eng Comput*. [Review / Meta-Analysis]
Shah AH (2025). [PMID: 41607726](https://pubmed.ncbi.nlm.nih.gov/41607726/). *CJC Pediatr Congenit Heart Dis*. [Other]
Xue Z (2025). [PMID: 41087327](https://pubmed.ncbi.nlm.nih.gov/41087327/). *Cell Discov*. [Basic Science / Preclinical]
Ueda Y (2025). [PMID: 40949535](https://pubmed.ncbi.nlm.nih.gov/40949535/). *Orthop J Sports Med*. [Case Report / Case Series]
Yan W (2024). [PMID: 38922829](https://pubmed.ncbi.nlm.nih.gov/38922829/). *J Drug Target*. [Review / Meta-Analysis]

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 6:18 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:97336

GARD

Genetic and Rare Diseases Info Center

GARD:19365

Questions for Your Care Team

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panner disease

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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