An area of necrotic bone in the mandible or maxilla.
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
The documentation surrounding osteonecrosis of the jaw is limited due to its relatively rare occurrence and the variability in clinical presentation. This rarity has resulted in fewer systematic studies, making it difficult to gather comprehensive data. Additionally, the lack of identified genetic factors further complicates the understanding of the condition.
To navigate osteonecrosis of the jaw, consider consulting with an oral and maxillofacial surgeon who specializes in bone disorders. They can provide insights into potential treatment options and management strategies. Additionally, explore clinical trial opportunities, as participating in research can provide access to new therapies. For more resources, visit the Genetic and Rare Diseases Information Center at rarediseases.info.nih.gov, which may offer further guidance and support.
There are currently 12 active clinical trials investigating various aspects of osteonecrosis of the jaw. Research includes the development of orphan drugs such as autologous adult live cultured osteoblasts and human allogeneic bone marrow-derived osteoblastic cells. For more information about these trials, you can visit ClinicalTrials.gov and search for osteonecrosis of the jaw.
Actionable guidance for navigating care for osteonecrosis of the jaw
To navigate osteonecrosis of the jaw, consider consulting with an oral and maxillofacial surgeon who specializes in bone disorders. They can provide insights into potential treatment options and management strategies. Additionally, explore clinical trial opportunities, as participating in research can provide access to new therapies. For more resources, visit the Genetic and Rare Diseases Information Center at rarediseases.info.nih.gov, which may offer further guidance and support.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Organizations with approved therapies for this disease
No approved therapies yet
Research is ongoing — 1 company has orphan drug designations for this disease
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.