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Ovarian endometrioid adenocarcinoma is a malignant epithelial tumor arising from the ovary. The packet definition states it accounts for 10% to 25% of all primary ovarian carcinomas. Grossly, the tumor may present as a cystic or solid mass; microscopically it closely resembles ordinary endometrial adenocarcinoma. A recognized subtype is ovarian endometrioid adenocarcinoma with squamous differentiation. The condition is catalogued in Orphanet and GARD (NIH).
Specific phenotypic data for ovarian endometrioid adenocarcinoma are not provided in this packet. Clinical presentations reflect the anatomical site and extent of tumor involvement, with features varying by disease stage and individual factors.
No known causal genes or inheritance patterns are identified in this packet. Ovarian endometrioid adenocarcinoma arises as an acquired malignancy; the molecular drivers are not characterized in the available data.
Detailed diagnostic criteria are not provided in this packet. Diagnosis involves identifying endometrioid adenocarcinoma histology arising from the ovary, with morphological features resembling endometrial adenocarcinoma. Definitive characterization relies on pathological examination.
No treatments have received FDA approval specifically for ovarian endometrioid adenocarcinoma as reflected in this packet. Treatment planning depends on disease stage, tumor characteristics, and individual health. Management typically involves a multidisciplinary oncology team and may include surgery, local or regional therapies, systemic treatment approaches, and supportive care. Treatment goals are individualized and may focus on curative intent or disease control.
26 trials found
The packet definition notes that, as a group, endometrioid ovarian carcinoma carries a prognosis approximately twice as favorable as that of serous or mucinous ovarian carcinoma. Outcomes depend on disease stage at diagnosis, tumor characteristics, and response to treatment.
Ovarian endometrioid adenocarcinoma is an active area of clinical investigation, with several ongoing clinical trials examining combination drug regimens, immunotherapy approaches, and targeted agents. Published research is substantial, with basic science and preclinical studies representing the dominant classification type. Current trial listings are available at ClinicalTrials.gov.
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 5:51 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
AI-curated news mentioning ovarian endometrioid adenocarcinoma
Updated Jun 8, 2026
A rare case study highlights ovarian endometrioid carcinoma presenting with presumed right ventricular intracardiac metastasis and thrombus. This finding underscores the unusual manifestations of gynecologic malignancies.