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A carcinoma that arises from the ovary and is characterized by the presence of malignant epithelial cells that resemble malignant urothelial cells. There is no morphologic evidence of a benign or borderline Brenner tumor component present.
Biomarker and diagnostic research for ovarian transitional cell carcinoma has been reported in the published literature.
9 clinical trials registered. Interventions under study include procedural interventions, drug therapy, other interventions, and biologic therapy. Pipeline includes 4 PHASE3, 3 PHASE2, 2 PHASE1. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT04739800](https://clinicaltrials.gov/study/NCT04739800) |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 11:28 PM UTC
Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents |
PHASE2 |
National Cancer Institute (NCI) |
UNKNOWN |
[NCT04092270](https://clinicaltrials.gov/study/NCT04092270) | A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer | PHASE1 | National Cancer Institute (NCI) | UNKNOWN |
[NCT02834013](https://clinicaltrials.gov/study/NCT02834013) | Nivolumab and Ipilimumab in Treating Patients With Rare Tumors | PHASE2 | National Cancer Institute (NCI) | ACTIVE_NOT_RECRUITING |
[NCT02068794](https://clinicaltrials.gov/study/NCT02068794) | MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer | PHASE1 | Mayo Clinic | UNKNOWN |
[NCT02446600](https://clinicaltrials.gov/study/NCT02446600) | Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer | PHASE3 | National Cancer Institute (NCI) | UNKNOWN |
144 publications have been identified in PubMed for ovarian transitional cell carcinoma. Research spans Basic Science / Preclinical (79%), Review / Meta-Analysis (14%), and Gene Therapy / Novel Therapeutics (4%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 99 | 79% |
Research summaries | 17 | 14% |
New treatment approaches | 5 | 4% |
Testing and diagnosis research | 2 | 2% |
Patient case studies | 1 | 1% |
Clinical study results | 1 | 1% |
Tsai CC (2026). [PMID: 41869454](https://pubmed.ncbi.nlm.nih.gov/41869454/). *J Cancer*. [Basic Science / Preclinical]
Feng C (2026). [PMID: 41850247](https://pubmed.ncbi.nlm.nih.gov/41850247/). *Cell Rep Med*. [Basic Science / Preclinical]
Liu Q (2026). [PMID: 41526347](https://pubmed.ncbi.nlm.nih.gov/41526347/). *Nat Commun*. [Basic Science / Preclinical]
Li W (2026). [PMID: 41271556](https://pubmed.ncbi.nlm.nih.gov/41271556/). *Adv Sci (Weinh)*. [Basic Science / Preclinical]
Gu HC (2026). [PMID: 41565641](https://pubmed.ncbi.nlm.nih.gov/41565641/). *Nat Commun*. [Basic Science / Preclinical]
He R (2026). [PMID: 41362744](https://pubmed.ncbi.nlm.nih.gov/41362744/). *Int J Biol Sci*. [Basic Science / Preclinical]
Naigaonkar A (2026). [PMID: 41308869](https://pubmed.ncbi.nlm.nih.gov/41308869/). *Life Sci*. [Basic Science / Preclinical]
Di Zhao (2025). [PMID: 40945198](https://pubmed.ncbi.nlm.nih.gov/40945198/). *Pathol Res Pract*. [Basic Science / Preclinical]
Silverstein J (2025). [PMID: 40501444](https://pubmed.ncbi.nlm.nih.gov/40501444/). *Future Oncol*. [Review / Meta-Analysis]
Dai C (2025). [PMID: 41202710](https://pubmed.ncbi.nlm.nih.gov/41202710/). *Cancer Genet*. [Basic Science / Preclinical]