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Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for painful legs and moving toes syndrome.
3 publications have been identified in PubMed for painful legs and moving toes syndrome. Research spans Case Report / Case Series (67%) and Review / Meta-Analysis (33%).
Fogoum Fogang Y (2025). [PMID: 41334603](https://pubmed.ncbi.nlm.nih.gov/41334603/). *Movement disorders clinical practice*. [Case Report / Case Series]
Tsalta-Mladenov M (2024). [PMID: 39585061](https://pubmed.ncbi.nlm.nih.gov/39585061/). *Neurology international*. [Review / Meta-Analysis]
Mimura Y (2024). [PMID: 38960725](https://pubmed.ncbi.nlm.nih.gov/38960725/). *Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:40 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center