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Perinatal asphyxia is described as a disorder caused by a lack of blood flow or gas exchange to or from the fetus in the period immediately before, during, or after the birth process. The condition is also referred to by names such as birth asphyxia, hypoxic-ischemic encephalopathy (HIE), asphyxia neonatorum, and intrapartum asphyxia. Orphanet-derived prevalence information in the packet places it in the uncommon category, at 1-9 in 100,000.
Specific clinical features, frequencies, and age of onset are not certified in this packet, so no symptom description is provided here.
The packet defines the condition by interrupted blood flow or gas exchange to or from the fetus around the time of birth. No genes are listed for this condition in the packet, and no inheritance pattern is recorded.
Diagnostic tests and criteria are not certified in this packet. A research record in the packet describes a planned study of early biomarkers of the impacts of perinatal asphyxia, which indicates that biomarker work is ongoing but does not describe an established diagnostic method.
Treatment coverage is not certified in this packet, and no FDA-approved treatments are recorded. FDA orphan drug designations exist for several investigational agents with indications that include neonatal hypoxic-ischemic encephalopathy or perinatal asphyxia; an orphan designation does not indicate approval, development status, or availability.
50 trials found
Prognosis is not certified in this packet.
The packet's ClinicalTrials.gov records for this condition include a not-yet-recruiting phase 2 study of intranasal stem cells for perinatal brain injury (UMC Utrecht) and a not-yet-recruiting multimodal biomarker study of the impacts of perinatal asphyxia (Amiens University Hospital). Many other records matched through the term perinatal concern maternal mental health and are not specific to this condition. Active clinical trials for this condition are listed on ClinicalTrials.gov.
Data assembled from 5 of 12 sources · Last updated Nov 4, 2026, 2:26 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center