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Peripheral Neuropathy — NIH Grants & Funding

Active and recent NIH-funded research on Peripheral Neuropathy. Data from NIH RePORTER, last 36 months.

MONDO:0005244

NIH-funded research on Peripheral Neuropathy

active grants

institutions

119

researchers

new in last 12 mo.

$86.8M in NIH funding over the last 36 months. Data from NIH RePORTER.

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Basic Science(45)

Basic ScienceZIACompleted

Helping to End Addiction Long-term (HEAL): Induced Pluripotent Stem Cell (iPSC)-Derived Cell Types for Pain, Addiction and Overdose

Simeonov, Anton·NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

$927,050 (FY2023)

Peripheral Neuropathy — NIH Grants & Funding

Basic Science(45)

Helping to End Addiction Long-term (HEAL): Induced Pluripotent Stem Cell (iPSC)-Derived Cell Types for Pain, Addiction and Overdose

Targeting neuronal transport to ameliorate vincristine neurotoxicity

Metabolic coupling between Schwann cells and axons is functionally distinct from myelination and is disrupted in obesity, prediabetes, and diabetes

The role of SARM1 in neuroinflammation-mediated axonal damage

Folding, Misfolding, and Function of PMP22

Neuroprotection for chemotherapy induced peripheral neuropathy

Mechanisms of Peripheral Nerve Injury and Recovery in a Zebrafish Demyelination Model

Role of ATAD3A in Lysosomal Homeostasis and Neurogenesis

microRNA regulation of NMNAT-mediated Neuroprotection against Peripheral Neuropathy and Chronic Pain

TLR-mediated Small Fiber Neuropathy

Translational(12)

Cannabidiol/Palmitoylethanolamide sublingual tablets for the treatment of Painful Diabetic Peripheral Neuropathy

A Novel LRP1 Agonist, SP16, as a Therapeutic Treatment in Preventing Chemotherapy-Induced Peripheral Neuropathy

Identification of novel targets for the treatment of chemotherapy-induced painful peripheral neuropathy

Identification of novel lead EphB1/2 tyrosine kinase inhibitors targeting peripheral neuropathic pain

Developing mechanism-based strategies to treat chemotherapy-induced peripheral neuropathy

Leveraging machine learning to improve risk prediction for chemotherapy inducedneuropathy

Prevention of paclitaxel-induced peripheral neuropathy with nilotinib

(PQ12) Enhancement of DNA repair in neurons via a targeted APE1 small molecule modifier to decrease and reverse chemotherapy-induced peripheral neuropathy (CIPN)

Pre-clinical validation of Phase II peptide LRP-1 agonist to treat and prevent chemotherapy induced peripheral neuropathy.

Development of novel Amadorins for Diabetic Peripheral Neuropathy

Clinical(29)

Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imaging

Development of Pathology-activated Drugs for Treatment of Neuropathic Pain

Functional and histological changes to peripheral innervation following spinal cord stimulation in patients with painful diabetic neuropathy

Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) Trial

Investigating the Pathogenic Role of Tubulin Post-translational Modifications in CIPN

Longitudinal assessment of the role of interoception in chemotherapy-induced peripheral neuropathy (CIPN) along the cancer chemotherapy continuum

Axonal transport and chemotherapy induced peripheral neuropathy

Investigating the role of MAP2 in chemotherapy-induced peripheral neurotoxicity

Investigating Peripheral Neuropathy in Spinocerebellar Ataxia Type 3

Sphingolipid Signaling and Chemotherapy-Induced Peripheral Neurotoxicity

Epi / Nat. History(2)

The Flint Neuropathy Study: assessing diagnostic and management gaps in a Black, low-income population-supplement

Risk Factors and Outcomes Associated with Late-Life Diabetic Peripheral Neuropathy

Gene/Cell Therapy(1)

Treatment of Chemotherapy-Induced Peripheral Neuropathy via Genetic Repression of Sodium Channels

Biomarker / Dx(4)

Non-invasive, quantitative microscopic biomarkers for chemotherapy-induced peripheral neuropathy

Biomarker development in patients with HNPP

Clinical biomarker for early prediction of chemotherapy-induced peripheral neuropathy

DDT-BMQ-000079 Establishing Performance Characteristics of the Epidermal Neurite Density (END) Biomarker to Assist Diagnosis of Small Fiber Neuropathy

Medical Device(8)

Evaluating the Effect of a Local Microvascular Tissue Graft Treatment in Rat Models of Diabetic Peripheral Neuropathy

Spinal cord stimulation for the attenuation of chemotherapy-induced peripheral neuropathy and enhanced chemotherapeutic efficacy

mHealth app for caregiver instruction in manual therapy for chemotherapy-induced peripheral neuropathy

Thermal Imaging Modality for Detection of Large and Small Fiber Diabetic Peripheral Neuropathy

Clinical investigation of topical delivery of a muscarinic receptor antagonist for the prevention of chemotherapy-induced peripheral neuropathy

Topic 447: Development and testing of a non-invasive cryo-device to prevent chemotherapy-induced peripheral neuropathy in hands and feet of cancer patients receiving Taxol for breast cancer.

mHealth app for caregiver instruction in manual therapy for chemotherapy-induced peripheral neuropathy

Use of a novel physiologic measure for the assessment and monitoring of vincristine induced peripheral neuropathy (VIPN) in children and adolescents.

Other(1)

Damage-associated molecular patterns in chemotherapy toxicity