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Phrynoderma is a form of follicular hyperkeratosis seen in young children and adolescents due to nutritional deficiencies. It is clinically characterized by discrete, follicular, skin-colored papules with keratotic plugs distributed over elbows, knees, extensor extremities, and buttocks.
No clinical trials have been registered for phrynoderma.
5 publications have been identified in PubMed for phrynoderma. Research spans Case Report / Case Series (60%), Review / Meta-Analysis (20%), and Epidemiology / Natural History (20%).
Melloni L (2026). [PMID: 41148586](https://pubmed.ncbi.nlm.nih.gov/41148586/). *Ital J Dermatol Venerol*. [Epidemiology / Natural History]
Abdolvand M (2025). [PMID: 39802360](https://pubmed.ncbi.nlm.nih.gov/39802360/). *Clin Case Rep*. [Case Report / Case Series]
Jing FZ (2025). [PMID: 39834723](https://pubmed.ncbi.nlm.nih.gov/39834723/). *JAAD Case Rep*. [Case Report / Case Series]
Verheyden MJ (2024). [PMID: 38877854](https://pubmed.ncbi.nlm.nih.gov/38877854/). *Med J Aust*. [Case Report / Case Series]
Sen Sarma M (2024). [PMID: 39181321](https://pubmed.ncbi.nlm.nih.gov/39181321/). *J Pediatr*. [Review / Meta-Analysis]
Data assembled from 2 of 12 sources · Last updated Sep 20, 2026, 5:49 AM UTC