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plague - Clinical Profile, Treatments & Trials | Kisho | Kisho

Rare Disease

plague

MONDO:0019095

Also known as:Yersiniosisblack deathinfection by Yersinia pestis

Find Clinical TrialsTrials

Overview

Plague is a severe bacterial infection caused by the gram-negative bacterium Yersinia pestis.

Treatments1 FDA approved

Clinical Trials3 registered · 1 recruiting

Diagnosis

Biomarker and diagnostic research for plague has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

1 FDA-approved treatment is available for plague, including CIPROFLOXACIN (CIPRO, approved 1997).

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

3 clinical trials registered, 1 recruiting. Interventions under study include biologic therapy, drug therapy, and other interventions. Pipeline includes 1 PHASE2, 1 PHASE1. Research is sponsored by a mix of industry and academic institutions.

361 publications have been identified in PubMed for plague. Kisho has analyzed 124 by research type. Research spans Basic Science / Preclinical (33%), Epidemiology / Natural History (31%), and Review / Meta-Analysis (19%).

Research Type	Count	% of Total
Laboratory research	41

Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 4:28 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:707

GARD

Genetic and Rare Diseases Info Center

GARD:18702

Questions for Your Care Team

→What are the benefits and potential side effects of CIPRO for managing plague?
→Are any of the 3 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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plague

Overview

Diagnosis

Treatment

Approved Therapies

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

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