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Poisoning — NIH Grants & Funding

Active and recent NIH-funded research on Poisoning. Data from NIH RePORTER, last 36 months.

MONDO:0029000

NIH-funded research on Poisoning

active grants

institutions

researchers

new in last 12 mo.

$77.9M in NIH funding over the last 36 months. Data from NIH RePORTER.

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Basic Science(12)

Basic ScienceR01Active

Dissecting the mechanisms underlying fentanyl-induced cardiorespiratory depression

Moron-Concepcion, Jose·WASHINGTON UNIVERSITY·SAINT LOUIS, MO

$671,732 (FY2025)

Poisoning — NIH Grants & Funding

Basic Science(12)

Dissecting the mechanisms underlying fentanyl-induced cardiorespiratory depression

Knowledge Warding Against Toxin Levels

Defining the Mechanism of Intoxication of the Clostridioides difficile Transferase

MALDI Imaging of Acute Organophosphate Exposure in KIKO Mice

Impaired Sleep as a Target for Intervention Following Acute Organophosphate Intoxication

A novel drug delivery system for the prevention and rescue of fentanyl and other opioid overdoses

Does lead (Pb) poisoning impair brain development by affecting how thyroid hormone gets into the brain?

Resolving the intoxication mechanism of botulinum neurotoxins using single molecule structural biology

Convergent mechanisms of respiratory dysregulation after seizures and alcohol poisoning

Covalent Inhibition as a Method to Counteract Botulinum Intoxication

Translational(18)

Antibody-based therapy for fentanyl-related opioid use disorder

A Novel Reversal Agent for Treatment of Overdose from the Combination of Fentanyl and Xylazine

NX90: A Treatment for Overdose Caused by High Potency Opioids

Novel therapeutic approaches to treatment of botulinum neurotoxin poisoning

Bacteriophage virus-like particle vaccines for fentanyl and heroin overdose

Long-acting aldicarb hydrolase as a medical countermeasure for aldicarb poisoning

Pregnenolone as a Treatment for Cannabis Intoxication

Negative allosteric modulation of mu opioid receptors to reverse fentanyl overdose

UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate Intoxication

Development of medication for the treatment of respiratory depression due to opioid (prescribed or illicit) overdose/multidrug (polysubstance) overdose in a hospital or community setting.

Clinical(6)

Development of the anti-fentanyl monoclonal antibody, CSX-1004, for prophylaxis against fentanyl and fentanyl analog overdose

Development of an intravenous CB1 antagonist for acute cannabinoid intoxication and cannabis hyperemesis syndrome

Optimization of Bile Sequestrants to Treat Superwarfarin Poisoning

ED-EXACT in Opioid Overdose: Emergency Department Evaluation of Xylazine-Associated Clinical Toxicity in Opioid Overdose

Therapeutic Agent for Rapid Reversal of Methamphetamine Intoxication

An oral therapeutic to treat intoxication by prescription and illicit stimulants

Epi / Nat. History(2)

Fentalog II: Medical Consequences of Novel Fentanyl Analog Overdose Using the Toxicology Investigators Consortium (TOXIC)

Prevention of Paralytic Shellfish Poisoning in Subsistence Shellfish Harvest Communities of Southeast Alaska

Biomarker / Dx(2)

Cell-free DNA Methylation Patterns and Mitochondrial Therapeutics in a Rodent Model of Organophosphate Poisoning

Antidote for inhaled CO poisoning based on mutationally engineered neuroglobin

Medical Device(2)

Hemoglobin-based antidotes for the treatment of carbon monoxide poisoning

Optimization of a Combined Drug and Delivery Device for Treatment of Cyanide Poisoning

Other(9)

Clinical Development of a Therapeutic Agent for Rapid Reversal of Methamphetamine Intoxication

Development of Cobinamide as a Cyanide Antidote: Completion of pre-IND Studies

Mechanisms of Cyanide-Induced Neurotoxicity and Purine Dysregulation

The ANTIDOTE Institute- Advancing New Toxicology Investigators in Drug abuse and Original Translational research Efforts

Optimization of a carbon monoxide (CO) sensing hemoprotein for applications as an antidote for CO poisoning and a biosensor for CO detection in living cells

Nucleic acid aptamers as interventions for developmental neurotoxicity

Development of TNX-1300 (Double Mutant Cocaine Esterase) for the Treatment of Life-Threatening Cocaine Intoxication

Targeting M1/M3 Muscarinic Receptors to Treat Gestational Pesticide Poisoning

Genetic Variation of Ultra-Potent Synthetic Opioid Sensitivity in Mice