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Polyvalvular heart disease syndrome is a recently described syndrome characterized by the combination of polyvalvular heart disease, short stature, facial anomalies and intellectual deficit.
Biomarker and diagnostic research for polyvalvular heart disease syndrome has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for polyvalvular heart disease syndrome.
154 publications have been identified in PubMed for polyvalvular heart disease syndrome. Research spans Review / Meta-Analysis (33%), Basic Science / Preclinical (24%), and Epidemiology / Natural History (16%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 51 | 33% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 12:51 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Laboratory research
37 |
24% |
Disease patterns and progression | 24 | 16% |
Clinical study results | 21 | 14% |
Patient case studies | 10 | 6% |
Testing and diagnosis research | 7 | 5% |
Other research | 2 | 1% |
New treatment approaches | 2 | 1% |
Pories WJ (2026). [PMID: 41910158](https://pubmed.ncbi.nlm.nih.gov/41910158/). *J Am Coll Surg*. [Review / Meta-Analysis]
Calcaterra V (2026). [PMID: 41917641](https://pubmed.ncbi.nlm.nih.gov/41917641/). *Adv Exp Med Biol*. [Review / Meta-Analysis]
Farrell C (2026). [PMID: 42043831](https://pubmed.ncbi.nlm.nih.gov/42043831/). *Alzheimers Dement*. [Review / Meta-Analysis]
Masiero S (2026). [PMID: 42041808](https://pubmed.ncbi.nlm.nih.gov/42041808/). *Brain Sci*. [Review / Meta-Analysis]
Goala P (2026). [PMID: 41165751](https://pubmed.ncbi.nlm.nih.gov/41165751/). *The Journal of clinical investigation*. [Review / Meta-Analysis]
Unknown (2026). [PMID: 42217196](https://pubmed.ncbi.nlm.nih.gov/42217196/). *Horm Res Paediatr*. [Other]
Li N (2026). [PMID: 41821986](https://pubmed.ncbi.nlm.nih.gov/41821986/). *Psychopharmacology bulletin*. [Clinical Trial Publication]
Nademanee K (2026). [PMID: 41738055](https://pubmed.ncbi.nlm.nih.gov/41738055/). *J Arrhythm*. [Review / Meta-Analysis]
Valdesalici A (2026). [PMID: 41580212](https://pubmed.ncbi.nlm.nih.gov/41580212/). *Psychol Sport Exerc*. [Review / Meta-Analysis]
Weeks LD (2026). [PMID: 41289141](https://pubmed.ncbi.nlm.nih.gov/41289141/). *Rheumatology (Oxford)*. [Review / Meta-Analysis]