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Porokeratosis plantaris palmaris et disseminata (PPPD) is a rare form of porokeratosis occurring mainly in adolescence and characterized by small pruritic or painful keratotic papules that first appear on the palms and soles, and may gradually become generalized.
Features include: Palmar telangiectasia, Porokeratosis, and Plantar telangiectasia.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Skin | 2 | Palmar telangiectasia, Plantar telangiectasia |
Biomarker and diagnostic research for porokeratosis plantaris palmaris et disseminata has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for porokeratosis plantaris palmaris et disseminata.
102 publications have been identified in PubMed for porokeratosis plantaris palmaris et disseminata. Research spans Case Report / Case Series (48%), Other (16%), and Review / Meta-Analysis (16%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 49 | 48% |
Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 9:50 PM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Other research
16 |
16% |
Research summaries | 16 | 16% |
New treatment approaches | 6 | 6% |
Testing and diagnosis research | 5 | 5% |
Laboratory research | 5 | 5% |
Disease patterns and progression | 3 | 3% |
Clinical study results | 2 | 2% |
Kaliyadan F (2026). [PMID: 42176708](https://pubmed.ncbi.nlm.nih.gov/42176708/). *J Am Acad Dermatol*. [Diagnostic / Biomarker]
Chen Y (2026). [PMID: 41773530](https://pubmed.ncbi.nlm.nih.gov/41773530/). *J Int Med Res*. [Review / Meta-Analysis]
Chen S (2026). [PMID: 40888583](https://pubmed.ncbi.nlm.nih.gov/40888583/). *Int J Dermatol*. [Case Report / Case Series]
Martini J (2026). [PMID: 41606785](https://pubmed.ncbi.nlm.nih.gov/41606785/). *Clin Exp Dermatol*. [Review / Meta-Analysis]
Reich D (2026). [PMID: 41996291](https://pubmed.ncbi.nlm.nih.gov/41996291/). *Int J Dermatol*. [Other]
Yang Y (2026). [PMID: 41240373](https://pubmed.ncbi.nlm.nih.gov/41240373/). *Br J Dermatol*. [Basic Science / Preclinical]
Jin S (2026). [PMID: 40434053](https://pubmed.ncbi.nlm.nih.gov/40434053/). *J Eur Acad Dermatol Venereol*. [Case Report / Case Series]
Del Puerto C (2026). [PMID: 41887924](https://pubmed.ncbi.nlm.nih.gov/41887924/). *J Cutan Pathol*. [Case Report / Case Series]
Zheng Y (2026). [PMID: 41387188](https://pubmed.ncbi.nlm.nih.gov/41387188/). *J Dermatol*. [Case Report / Case Series]
Liu W (2026). [PMID: 42139042](https://pubmed.ncbi.nlm.nih.gov/42139042/). *JAMA Dermatol*. [Case Report / Case Series]