Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

pouchitis - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

pouchitis

MONDO:0005312

Find Clinical TrialsTrials

Overview

Acute inflammation in the intestinal mucosa of the continent ileal reservoir (or pouch) in patients who have undergone ileostomy and restorative proctocolectomy (proctocolectomy, restorative).

TreatmentsNo approved treatments · 7 in pipeline

Clinical Trials13 registered · 6 recruiting

Diagnosis

Biomarker and diagnostic research for pouchitis has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

No approved treatments are currently available for pouchitis. An additional 7 compounds hold orphan drug designation.

Orphan Drug Designations

While no drugs are FDA-approved specifically for pouchitis, some of the following designated compounds may be used off-label in clinical practice. Treatment decisions should be made in consultation with a specialist familiar with this condition.

The following drugs have received orphan drug designation from the FDA for pouchitis. Orphan designation reflects regulatory interest and does not indicate approval for treatment.

Brand Name	Generic Name	Sponsor

Prognosis

Estimated prevalence: 1-5 in 10,000 (Uncommon).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

13 clinical trials registered, 6 recruiting. Interventions under study include drug therapy, other interventions, and medical devices. Pipeline includes 5 PHASE4, 2 PHASE3, 3 PHASE2. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT06443502](https://clinicaltrials.gov/study/NCT06443502)

Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 8:40 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:217067

GARD

Genetic and Rare Diseases Info Center

GARD:20510

Questions for Your Care Team

→Are any of the 13 active clinical trials a good fit for my situation?
→With 7 compounds in the orphan drug pipeline, which are furthest along in development and which clinical trials should I be aware of?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Research Type	Count	% of Total
Research summaries	49	37%
Disease patterns and progression	29	22%
Clinical study results	18	14%
Other research	9	7%
Patient case studies	9	7%
Laboratory research	7	5%
Testing and diagnosis research	6	5%
New treatment approaches	4	3%

pouchitis

Overview

Diagnosis

Treatment

Orphan Drug Designations

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications