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Prader-Willi-like syndrome - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

Prader-Willi-like syndrome

MONDO:0018354

Also known as:PWS-like

Find Clinical TrialsTrials

Overview

Prader-Willi-like syndrome is a rare, genetic, endocrine disease characterized by manifestations of a Prader-Willi syndrome phenotype (including obesity, hyperphagia, hypotonia, psychomotor delay, intellectual disability, small hands/feet, hypogonadism, growth hormone deficiency and characteristic facial features) occurring in the absence of 15q11-q13 genomic abnormalities.

OnsetINFANTILE

Clinical Trials1 registered · 1 recruiting

ResearchLimited published research (7 articles)

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.

7 publications have been identified in PubMed for Prader-Willi-like syndrome. Research spans Review / Meta-Analysis (29%), Case Report / Case Series (29%), and Basic Science / Preclinical (29%).

Recent Publications

Mohammed I (2026). [PMID: 41516406](https://pubmed.ncbi.nlm.nih.gov/41516406/). *International journal of molecular sciences*. [Basic Science / Preclinical]
Bokov P (2025). [PMID: 39745485](https://pubmed.ncbi.nlm.nih.gov/39745485/). *Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine*. [Case Report / Case Series]
Saeed S (2025). [PMID: 40549565](https://pubmed.ncbi.nlm.nih.gov/40549565/). *The Journal of clinical investigation*. [Gene Therapy / Novel Therapeutics]
Beales PL (2025). [PMID: 40186386](https://pubmed.ncbi.nlm.nih.gov/40186386/). *Obes Rev*. [Review / Meta-Analysis]

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:02 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:398073

GARD

Genetic and Rare Diseases Info Center

GARD:21641

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Prader-Willi-like syndrome

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team