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Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma is a rare form of primary cutaneous T-cell lymphoma characterized by rapidly progressing, localized or disseminated nodules, tumors or eczematous skin lesions. It has a particularly aggressive clinical course with a high tendency to spread, in advanced stages, to extracutaneous locations (the central nervous system, lung, testes). Lymph nodes are often spared.
No clinical trials have been registered for primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma.
14 publications have been identified in PubMed for primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma. Research spans Case Report / Case Series (57%), Review / Meta-Analysis (29%), and Other (7%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 8 | 57% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 9:41 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries |
4 |
29% |
Other research | 1 | 7% |
Laboratory research | 1 | 7% |
Schukow C (2026). [PMID: 36944007](https://pubmed.ncbi.nlm.nih.gov/36944007/). *Unknown Journal*. [Review / Meta-Analysis]
Singh AP (2026). [PMID: 41371249](https://pubmed.ncbi.nlm.nih.gov/41371249/). *J Cutan Pathol*. [Case Report / Case Series]
Meng C (2026). [PMID: 41400112](https://pubmed.ncbi.nlm.nih.gov/41400112/). *J Cutan Pathol*. [Case Report / Case Series]
Jaramillo J (2025). [PMID: 41227238](https://pubmed.ncbi.nlm.nih.gov/41227238/). *J Clin Med*. [Case Report / Case Series]
Chennareddy S (2025). [PMID: 39133553](https://pubmed.ncbi.nlm.nih.gov/39133553/). *Br J Dermatol*. [Basic Science / Preclinical]
Nikakis J (2025). [PMID: 41607964](https://pubmed.ncbi.nlm.nih.gov/41607964/). *Cureus*. [Case Report / Case Series]
Inoue Y (2025). [PMID: 39894488](https://pubmed.ncbi.nlm.nih.gov/39894488/). *Intern Med*. [Case Report / Case Series]
Cheng P (2025). [PMID: 40613169](https://pubmed.ncbi.nlm.nih.gov/40613169/). *Zhongguo Shi Yan Xue Ye Xue Za Zhi*. [Case Report / Case Series]
Swallow MA (2024). [PMID: 39272944](https://pubmed.ncbi.nlm.nih.gov/39272944/). *Cancers (Basel)*. [Review / Meta-Analysis]
Wei R (2024). [PMID: 38263572](https://pubmed.ncbi.nlm.nih.gov/38263572/). *Int J Dermatol*. [Case Report / Case Series]