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primary cutaneous diffuse large B-cell lymphoma, Leg type - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

primary cutaneous diffuse large B-cell lymphoma, Leg type

MONDO:0006383

Also known as:PCDLBCL,LT

Find Clinical TrialsTrials

Overview

An aggressive primary cutaneous B-cell lymphoma, usually involving the lower leg. It is composed of a generally monotonous proliferation of immunoblasts, or less frequently centroblasts, with few admixed reactive cells. This type of lymphoma occurs most often in elderly women who present with rapidly growing tumors, usually on one or both legs. Dissemination to extracutaneous sites is frequent. Treatment with combination chemotherapy is usually required.

Clinical Trials6 registered · 1 recruiting

Diagnosis

Biomarker and diagnostic research for primary cutaneous diffuse large B-cell lymphoma, Leg type has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

6 clinical trials registered, 1 recruiting. Interventions under study include drug therapy, biologic therapy, procedural interventions, and other interventions. Pipeline includes 6 PHASE2. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT03038672](https://clinicaltrials.gov/study/NCT03038672)

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 4:32 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:178544

GARD

Genetic and Rare Diseases Info Center

GARD:20160

Questions for Your Care Team

→Are any of the 6 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	15	42%
Research summaries	12	33%
Other research	3	8%
Disease patterns and progression	3	8%
Laboratory research	2	6%
Testing and diagnosis research	1	3%

primary cutaneous diffuse large B-cell lymphoma, Leg type

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications