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Features include: Complete heart block with narrow QRS complexes, Syncope, Atrioventricular block, and Sudden cardiac death and 2 more.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 4 | Complete heart block with narrow QRS complexes, Atrioventricular block, Sudden cardiac death |
Biomarker and diagnostic research for progressive familial heart block type II has been reported in the published literature.
No clinical trials have been registered for progressive familial heart block type II.
10 publications have been identified in PubMed for progressive familial heart block type II. Research spans Basic Science / Preclinical (33%), Review / Meta-Analysis (22%), and Case Report / Case Series (22%).
Muharram M (2026). [PMID: 41582218](https://pubmed.ncbi.nlm.nih.gov/41582218/). *Journal of medical case reports*. [Review / Meta-Analysis]
Argirò A (2025). [PMID: 39665521](https://pubmed.ncbi.nlm.nih.gov/39665521/). *ESC heart failure*. [Epidemiology / Natural History]
Marcoux E (2025). [PMID: 40421533](https://pubmed.ncbi.nlm.nih.gov/40421533/). *Circulation. Arrhythmia and electrophysiology*. [Basic Science / Preclinical]
Tahir UA (2025). [PMID: 40509996](https://pubmed.ncbi.nlm.nih.gov/40509996/). *Circulation. Genomic and precision medicine*. [Basic Science / Preclinical]
Li PK (2025). [PMID: 40814615](https://pubmed.ncbi.nlm.nih.gov/40814615/). *Kidney international reports*. [Review / Meta-Analysis]
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 8:31 AM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
Pimentel J (2024). [PMID: 38978913](https://pubmed.ncbi.nlm.nih.gov/38978913/). *Cureus*. [Case Report / Case Series]
Westwood M (2024). [PMID: 39023142](https://pubmed.ncbi.nlm.nih.gov/39023142/). *Health technology assessment (Winchester, England)*. [Diagnostic / Biomarker]
Belcher AM (2024). [PMID: 39239135](https://pubmed.ncbi.nlm.nih.gov/39239135/). *European heart journal. Case reports*. [Case Report / Case Series]
Sá da Bandeira D (2024). [PMID: 39589268](https://pubmed.ncbi.nlm.nih.gov/39589268/). *Development (Cambridge, England)*. [Basic Science / Preclinical]
AI-curated news mentioning progressive familial heart block type II
Updated Jul 28, 2026
A study highlights the diagnostic potential of anti-PM-Scl 100 antibodies in identifying inaugural complete heart block in patients with anti-SSA negative systemic lupus erythematosus. This research may enhance diagnostic accuracy for this rare condition.
A new study explores emergency pacing techniques for neonatal complete heart block, highlighting innovative approaches to improve patient outcomes. This research could influence future clinical practices in managing this rare condition.