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protoplasmic astrocytoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

protoplasmic astrocytoma

MONDO:0016687

Also known as:protoplasmic astrocytic tumorprotoplasmic astrocytic tumourprotoplasmic astrocytoma (morphologic abnormality)

Overview

A rare variant of diffuse astrocytoma. It is predominantly composed of neoplastic astrocytes showing a small cell body with few, flaccid processes with a low content of glial filaments and scant GFAP expression. This lesion is not well defined and is considered by some authors as an occasional histopathological feature rather than a reproducibly identifiable variant. When occurring in children, this neoplasm may be difficult to separate from pilocytic juvenile astrocytoma. (Adapted from WHO)

Diagnosis

Biomarker and diagnostic research for protoplasmic astrocytoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for protoplasmic astrocytoma.

209 publications have been identified in PubMed for protoplasmic astrocytoma. Research spans Basic Science / Preclinical (63%), Gene Therapy / Novel Therapeutics (18%), and Review / Meta-Analysis (9%).

Research Type	Count	% of Total
Laboratory research	118	63%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:40 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:251598

GARD

Genetic and Rare Diseases Info Center

GARD:20707

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protoplasmic astrocytoma

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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