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diffuse astrocytoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

diffuse astrocytoma

MONDO:0016686

Also known as:WHO grade II astrocytomaastrocytoma, diffuseastrocytoma, diffuse, malignant

Find Clinical TrialsTrials

Overview

A low-grade (WHO grade II) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These lesions typically affect young adults and have a tendency for progression to anaplastic astrocytoma and glioblastoma. Based on the IDH genes mutation status, diffuse astrocytomas are classified as IDH-mutant, IDH-wildtype, and not otherwise specified.

Clinical Trials11 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for diffuse astrocytoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

11 clinical trials registered, 3 recruiting. Interventions under study include drug therapy, procedural interventions, other interventions, and biologic therapy. Pipeline includes 1 PHASE4, 3 PHASE2, 4 PHASE1. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT07468136](https://clinicaltrials.gov/study/NCT07468136)

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 11:42 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:251595

GARD

Genetic and Rare Diseases Info Center

GARD:5907

Questions for Your Care Team

→Are any of the 11 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Laboratory research	36	33%
Research summaries	27	25%
Patient case studies	23	21%
Clinical study results	8	7%
Testing and diagnosis research	7	6%
Disease patterns and progression	4	4%
New treatment approaches	2	2%
Other research	1	1%

diffuse astrocytoma

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications