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A WHO grade II tumor composed of a conspicuous mixture of two distinct neoplastic cell types morphologically resembling the tumor cells in oligodendroglioma and diffuse astrocytoma. (WHO)
Biomarker and diagnostic research for oligoastrocytoma has been reported in the published literature.
6 clinical trials registered, 1 recruiting. Interventions under study include drug therapy, procedural interventions, other interventions, and biologic therapy. Pipeline includes 3 PHASE2, 3 PHASE1. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT02800486](https://clinicaltrials.gov/study/NCT02800486) |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 3:38 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA |
PHASE2 |
Northwell Health |
RECRUITING |
[NCT07031765](https://clinicaltrials.gov/study/NCT07031765) | Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma | PHASE1 | University of Florida | ACTIVE_NOT_RECRUITING |
[NCT02192359](https://clinicaltrials.gov/study/NCT02192359) | Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas | PHASE1 | City of Hope Medical Center | UNKNOWN |
[NCT03152318](https://clinicaltrials.gov/study/NCT03152318) | A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 | PHASE1 | Dana-Farber Cancer Institute | UNKNOWN |
[NCT03180502](https://clinicaltrials.gov/study/NCT03180502) | Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma | PHASE2 | NRG Oncology | UNKNOWN |
218 publications have been identified in PubMed for oligoastrocytoma. Research spans Review / Meta-Analysis (30%), Case Report / Case Series (18%), and Basic Science / Preclinical (16%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 65 | 30% |
Patient case studies | 39 | 18% |
Laboratory research | 35 | 16% |
Testing and diagnosis research | 34 | 16% |
Disease patterns and progression | 23 | 11% |
Clinical study results | 12 | 6% |
New treatment approaches | 6 | 3% |
Other research | 4 | 2% |
Hoogstrate Y (2026). [PMID: 41850239](https://pubmed.ncbi.nlm.nih.gov/41850239/). *Cell Rep Med*. [Gene Therapy / Novel Therapeutics]
Peters KB (2026). [PMID: 41201564](https://pubmed.ncbi.nlm.nih.gov/41201564/). *CNS Drugs*. [Review / Meta-Analysis]
Starc MT (2026). [PMID: 42230057](https://pubmed.ncbi.nlm.nih.gov/42230057/). *Radiol Clin North Am*. [Review / Meta-Analysis]
Tork CA (2026). [PMID: 32644610](https://pubmed.ncbi.nlm.nih.gov/32644610/). *Unknown Journal*. [Basic Science / Preclinical]
M YK (2026). [PMID: 42150140](https://pubmed.ncbi.nlm.nih.gov/42150140/). *Neurology*. [Case Report / Case Series]
Mahtab P (2026). [PMID: 41914105](https://pubmed.ncbi.nlm.nih.gov/41914105/). *Mymensingh Med J*. [Epidemiology / Natural History]
Martell E (2026). [PMID: 41825848](https://pubmed.ncbi.nlm.nih.gov/41825848/). *Cancer Lett*. [Review / Meta-Analysis]
Ge Z (2026). [PMID: 41242200](https://pubmed.ncbi.nlm.nih.gov/41242200/). *Surgical oncology*. [Review / Meta-Analysis]
Verma P (2026). [PMID: 42081703](https://pubmed.ncbi.nlm.nih.gov/42081703/). *Clin Nucl Med*. [Review / Meta-Analysis]
von Polenz I (2026). [PMID: 40916123](https://pubmed.ncbi.nlm.nih.gov/40916123/). *Clin Nucl Med*. [Case Report / Case Series]