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ptosis-vocal cord paralysis syndrome - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

ptosis-vocal cord paralysis syndrome

MONDO:0008665

Also known as:tucker syndromecongenital bilateral recurrent nerve paralysis and ptosisptosis vocal cord paralysis

Overview

Ptosis-vocal cord paralysis syndrome is a rare, hereditary disorder with ptosis characterized by the combination of congenital bilateral recurrent laryngeal nerve paralysis and congenital bilateral ptosis. There have been no further descriptions in the literature since 1983.

GeneticsAutosomal dominant

Clinical Presentation

Features include: Vocal cord paralysis and Bilateral ptosis.

Organ System	Phenotype Count	Example Features
Eyes	1	Bilateral ptosis

Explore clinical features

Diagnosis

Biomarker and diagnostic research for ptosis-vocal cord paralysis syndrome has been reported in the published literature.

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for ptosis-vocal cord paralysis syndrome.

208 publications have been identified in PubMed for ptosis-vocal cord paralysis syndrome. Kisho has analyzed 127 by research type. Research spans Case Report / Case Series (59%), Review / Meta-Analysis (16%), and Basic Science / Preclinical (9%).

Research Type	Count	% of Total
Patient case studies	75	59%

Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 6:20 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:193240

Orphanet

European rare disease database

Orphanet:2997

GARD

Genetic and Rare Diseases Info Center

GARD:427

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
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ptosis-vocal cord paralysis syndrome

Overview

Clinical Presentation

Explore clinical features

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

OMIM

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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