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Biomarker and diagnostic research for pure or complex hereditary spastic paraplegia has been reported in the published literature.
No clinical trials have been registered for pure or complex hereditary spastic paraplegia.
247 publications have been identified in PubMed for pure or complex hereditary spastic paraplegia. Kisho has analyzed 44 by research type. Research spans Basic Science / Preclinical (36%), Review / Meta-Analysis (20%), and Epidemiology / Natural History (20%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 16 | 36% |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 10:52 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries |
9 |
20% |
Disease patterns and progression | 9 | 20% |
Patient case studies | 5 | 11% |
Testing and diagnosis research | 2 | 5% |
Other research | 1 | 2% |
Clinical study results | 1 | 2% |
New treatment approaches | 1 | 2% |
Esener Z (2026). [PMID: 41808431](https://pubmed.ncbi.nlm.nih.gov/41808431/). *Int J Dev Neurosci*. [Review / Meta-Analysis]
Nolasco GA (2026). [PMID: 41000004](https://pubmed.ncbi.nlm.nih.gov/41000004/). *Ann Clin Transl Neurol*. [Epidemiology / Natural History]
Schmidt HJD (2026). [PMID: 41199121](https://pubmed.ncbi.nlm.nih.gov/41199121/). *Ann Clin Transl Neurol*. [Epidemiology / Natural History]
Agianda HAP (2026). [PMID: 41491634](https://pubmed.ncbi.nlm.nih.gov/41491634/). *Ann Clin Transl Neurol*. [Diagnostic / Biomarker]
Akarsu Ş (2026). [PMID: 41797006](https://pubmed.ncbi.nlm.nih.gov/41797006/). *J Neurochem*. [Basic Science / Preclinical]
Sotelo I (2026). [PMID: 42222243](https://pubmed.ncbi.nlm.nih.gov/42222243/). *Case Rep Anesthesiol*. [Case Report / Case Series]
Schwartz R (2025). [PMID: 40064387](https://pubmed.ncbi.nlm.nih.gov/40064387/). *Am J Ophthalmol*. [Basic Science / Preclinical]
Cashman CR (2025). [PMID: 40400204](https://pubmed.ncbi.nlm.nih.gov/40400204/). *Ann Clin Transl Neurol*. [Basic Science / Preclinical]
Shi Y (2025). [PMID: 39468830](https://pubmed.ncbi.nlm.nih.gov/39468830/). *Mov Disord*. [Basic Science / Preclinical]
Ferese R (2025). [PMID: 40562529](https://pubmed.ncbi.nlm.nih.gov/40562529/). *J Med Genet*. [Epidemiology / Natural History]