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rapidly involuting congenital hemangioma (RICH) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

rapidly involuting congenital hemangioma

MONDO:0015404

Also known as:RICH

Overview

Rapidly involuting congenital hemangiomas (RICH) are a distinctive type of congenital hemangioma that are fully formed in utero and differ from non-involuting congenital haemangiomas (NICH) mainly because they undergo rapid postnatal involution.

ResearchLimited published research (3 articles)

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include always present findings: Hemangioma; and common findings: Midfrontal capillary hemangioma, Subcutaneous calcification, Perineal hemangioma, and Visible small blood vessels on skin (telangiectasia of the skin). 13 total HPO annotations.

Organ System	Phenotype Count	Example Features
Skin	2	Subcutaneous calcification, Visible small blood vessels on skin (telangiectasia of the skin)

Prognosis

Phenotype severity distribution: 1 always present feature, 4 common features.

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for rapidly involuting congenital hemangioma.

4 publications have been identified in PubMed for rapidly involuting congenital hemangioma. Kisho has analyzed 3 by research type. Research spans Case Report / Case Series (100%).

Recent Publications

Santarelli A (2026). [PMID: 41911199](https://pubmed.ncbi.nlm.nih.gov/41911199/). *Rev Fac Cien Med Univ Nac Cordoba*. [Case Report / Case Series]
Kudo M (2025). [PMID: 40161083](https://pubmed.ncbi.nlm.nih.gov/40161083/). *Cureus*. [Case Report / Case Series]
Hu Y (2024). [PMID: 38679897](https://pubmed.ncbi.nlm.nih.gov/38679897/). *Am J Case Rep*. [Case Report / Case Series]

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 6:17 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:141184

GARD

Genetic and Rare Diseases Info Center

GARD:19958

Questions for Your Care Team

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rapidly involuting congenital hemangioma

Overview

Clinical Presentation

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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