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A rare, clinically heterogeneous, multisystemic inflammatory disease characterized by inflammation of the cartilage and proteoglycan rich structures leading to cartilage damage with joint, ocular and cardiovascular involvement.
Biomarker and diagnostic research for relapsing polychondritis has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
4 clinical trials registered, 4 recruiting. Interventions under study include drug therapy, other interventions, and biologic therapy. Pipeline includes 1 PHASE2, 1 PHASE1. Research is primarily sponsored by academic and government institutions.
148 publications have been identified in PubMed for relapsing polychondritis. Kisho has analyzed 113 by research type. Research spans Case Report / Case Series (50%), Review / Meta-Analysis (26%), and Other (6%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 57 |
Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 7:12 PM UTC
Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.
European rare disease database
Genetic and Rare Diseases Info Center
50%
Research summaries | 29 | 26% |
Other research | 7 | 6% |
Testing and diagnosis research | 7 | 6% |
Clinical study results | 7 | 6% |
Disease patterns and progression | 6 | 5% |
Zhang X (2026). [PMID: 41173789](https://pubmed.ncbi.nlm.nih.gov/41173789/). *Ann Rheum Dis*. [Other]
Fujiwara K (2026). [PMID: 41418585](https://pubmed.ncbi.nlm.nih.gov/41418585/). *Auris Nasus Larynx*. [Case Report / Case Series]
Chung SW (2026). [PMID: 41753295](https://pubmed.ncbi.nlm.nih.gov/41753295/). *J Clin Med*. [Case Report / Case Series]
Nigro A (2026). [PMID: 41529578](https://pubmed.ncbi.nlm.nih.gov/41529578/). *Med Clin (Barc)*. [Other]
Magalhães JN (2026). [PMID: 41728517](https://pubmed.ncbi.nlm.nih.gov/41728517/). *Cureus*. [Case Report / Case Series]
Bonnan M (2026). [PMID: 42112400](https://pubmed.ncbi.nlm.nih.gov/42112400/). *Front Immunol*. [Review / Meta-Analysis]
Kim H (2026). [PMID: 41850228](https://pubmed.ncbi.nlm.nih.gov/41850228/). *Korean J Intern Med*. [Case Report / Case Series]
Shinners O (2026). [PMID: 42082356](https://pubmed.ncbi.nlm.nih.gov/42082356/). *Thorax*. [Clinical Trial Publication]
Dari MA (2026). [PMID: 41968374](https://pubmed.ncbi.nlm.nih.gov/41968374/). *J Med Case Rep*. [Case Report / Case Series]
Stonick K (2026). [PMID: 41235806](https://pubmed.ncbi.nlm.nih.gov/41235806/). *Arthritis Care Res (Hoboken)*. [Review / Meta-Analysis]
AI-curated news mentioning relapsing polychondritis
Updated Aug 11, 2026
Recent research highlights immune dysregulation and enhanced monocyte-centric communication in relapsing polychondritis through single-cell profiling. This study provides insights into the immune mechanisms underlying the disease, potentially guiding future therapeutic strategies.