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A myopathy that is characterized by muscle breakdown (rhabdomyolysis), heat and exertion-related muscle pain (myalgia) and cramping symptoms, severe muscle pain, sudden elevation and subsequent fall of serum creatine phosphokinase levels and products of muscle breakdown in the urine (myoglobinuria). Associated with RYR1 variations. Rhabdomyolysis is associated with a range of external triggers, including strenuous exercise beyond the limit of fatigue, heat stress, illicit drug or alcohol abuse, use of supplements or certain medications, recent viral illness or muscle trauma.
No clinical trials have been registered for rhabdomyolysis-myalgia syndrome.
1 publication has been identified in PubMed for rhabdomyolysis-myalgia syndrome. Research spans Review / Meta-Analysis (100%).
Richert Q (2026). [PMID: 41619932](https://pubmed.ncbi.nlm.nih.gov/41619932/). *Chest*. [Review / Meta-Analysis]
Data assembled from 2 of 12 sources · Last updated Sep 21, 2026, 12:36 AM UTC
AI-curated news mentioning rhabdomyolysis-myalgia syndrome
Updated Aug 21, 2026
A case report highlights fenofibrate-associated rhabdomyolysis leading to acute kidney injury requiring dialysis, showcasing atypical clinical manifestations. This literature review may inform clinicians about rare complications linked to fenofibrate treatment.
A case report highlights severe systemic myotoxicity and massive rhabdomyolysis following Ovophis anitae envenomation. This research contributes to understanding the toxicological effects of snake bites, particularly in rare cases.
Recent research highlights the association between acute Legionella infection and the development of rhabdomyolysis and acute kidney injury. This study underscores the need for awareness of these complications in clinical settings.