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rheumatic fever (ARF) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

rheumatic fever

MONDO:0017767

Also known as:ARFRHF - rheumatic feveracute rheumatic fever

Find Clinical TrialsTrials

Overview

A post-bacterial multisystem inflammatory disease occurring as a post-infectious, nonsuppurative sequela of untreated streptococcus pyogenes (Group A streptococcus [GAS]) pharyngitis, and mainly occurs in individuals aged 5 to 15 years. The most common presenting signs are fever, migratory polyarthritis and carditis.

Clinical Trials11 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for rheumatic fever has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

11 clinical trials registered, 3 recruiting. Interventions under study include other interventions and drug therapy. Pipeline includes 1 PHASE3, 3 NA. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT06259006](https://clinicaltrials.gov/study/NCT06259006)

Data assembled from 4 of 12 sources · Last updated Sep 17, 2026, 7:19 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:3099

GARD

Genetic and Rare Diseases Info Center

GARD:5699

Questions for Your Care Team

→Are any of the 11 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Research summaries	48	36%
Disease patterns and progression	33	24%
Patient case studies	22	16%
Other research	15	11%
Testing and diagnosis research	6	4%
Laboratory research	6	4%
Clinical study results	5	4%

rheumatic fever

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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