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selective immunoglobulin deficiency disease - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

selective immunoglobulin deficiency disease

MONDO:0003739

Also known as:selective Immunoglobulin isotype deficiency

Overview

A broad classification of dysgammaglobulinemias characterized by low or undetectable serum levels of one of the five immunoglobulin classes. Deficiencies of immunoglobulins present variably according to isotype. Selective deficiencies may be caused by decreased or inefficient production from progenitor B cells without any corresponding decreases in the other isotypes. The clinical course and prognosis is dependent upon the severity of the selective deficiency and associated morbidity.

Diagnosis

Biomarker and diagnostic research for selective immunoglobulin deficiency disease has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for selective immunoglobulin deficiency disease.

134 publications have been identified in PubMed for selective immunoglobulin deficiency disease. Research spans Review / Meta-Analysis (23%), Basic Science / Preclinical (23%), and Epidemiology / Natural History (16%).

Research Type	Count	% of Total
Research summaries	31	23%

Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 1:05 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

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selective immunoglobulin deficiency disease

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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