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A rare variant of seminoma characterized by the presence of three cell types: round cells with eosinophilic cytoplasm, small cells with dark nucleus and a small amount of cytoplasm, and mono-or multinucleated giant cells. The neoplastic cells are not cohesive. There is an edematous stroma present; lymphocytic infiltrates are rarely seen. Most patients are older males.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for spermatocytic seminoma.
2 publications have been identified in PubMed for spermatocytic seminoma. Research spans Case Report / Case Series (50%) and Basic Science / Preclinical (50%).
Saito M (2025). [PMID: 41185729](https://pubmed.ncbi.nlm.nih.gov/41185729/). *IJU case reports*. [Case Report / Case Series]
Lobo J (2024). [PMID: 38782099](https://pubmed.ncbi.nlm.nih.gov/38782099/). *Human pathology*. [Basic Science / Preclinical]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 7:34 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center