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squamous cell carcinoma of gallbladder and extrahepatic biliary tract - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

squamous cell carcinoma of gallbladder and extrahepatic biliary tract

MONDO:0018537

Also known as:squamous cell carcinoma of gallblader and EBT

Overview

Squamous cell carcinoma of the gallbladder and extrahepatic biliary tract is a rare hepatic and biliary tract tumor, arising either in the gallbladder itself or in the epithelium lining the extrahepatic biliary tree, the cystic duct and peribiliary glands. It is characterized by a substantial keratinization with abundant keratohyalin pearls and central deposition of dense keratin material within infiltrative nests and locally aggressive nature. In the early stages of the disease symptoms are vague and nonspecific (abdominal pain, jaundice and vomiting). In the advanced stages it may present with a bulky tumor and symptoms of adjacent organ involvement.

ResearchLimited published research (4 articles)

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for squamous cell carcinoma of gallbladder and extrahepatic biliary tract.

4 publications have been identified in PubMed for squamous cell carcinoma of gallbladder and extrahepatic biliary tract. Research spans Basic Science / Preclinical (50%), Other (25%), and Case Report / Case Series (25%).

Recent Publications

Vijay V (2025). [PMID: 40353839](https://pubmed.ncbi.nlm.nih.gov/40353839/). *Cancer discovery*. [Basic Science / Preclinical]
Ruffat A (2025). [PMID: 40220611](https://pubmed.ncbi.nlm.nih.gov/40220611/). *European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology*. [Case Report / Case Series]
Rikitake R (2025). [PMID: 40376725](https://pubmed.ncbi.nlm.nih.gov/40376725/). *Pathol Int*. [Other]
Vijay V (2024). [PMID: 39026794](https://pubmed.ncbi.nlm.nih.gov/39026794/). *bioRxiv : the preprint server for biology*. [Basic Science / Preclinical]

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:38 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:424996

GARD

Genetic and Rare Diseases Info Center

GARD:21792

Questions for Your Care Team

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squamous cell carcinoma of gallbladder and extrahepatic biliary tract

Overview

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team