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steroid-responsive encephalopathy associated with autoimmune thyroiditis - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

steroid-responsive encephalopathy associated with autoimmune thyroiditis

MONDO:0019385

Also known as:steroid-responsive encephalopathy associated with thyroid diseaseSREATHashimoto encephalitis

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Overview

Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a rare, acquired, neurological disease characterized by encephalopathy associated with elevated antithyroid antibodies, in the absence of other causes. Clinical presentation varies from minor cognitive impairment to status epilepticus and coma, and frequently includes seizures, confusion, speech disorder, memory impairment, ataxia and psychiatric manifestations.

Clinical Trials3 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for steroid-responsive encephalopathy associated with autoimmune thyroiditis has been reported in the published literature.

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

3 clinical trials registered, 3 recruiting. Interventions under study include drug therapy and other interventions. Pipeline includes 1 PHASE2, 1 NA. Research is primarily sponsored by academic and government institutions.

158 publications have been identified in PubMed for steroid-responsive encephalopathy associated with autoimmune thyroiditis. Research spans Review / Meta-Analysis (33%), Case Report / Case Series (23%), and Epidemiology / Natural History (22%).

Research Type	Count	% of Total
Research summaries	52

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 12:52 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:83601

GARD

Genetic and Rare Diseases Info Center

GARD:8570

Questions for Your Care Team

→Are any of the 3 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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steroid-responsive encephalopathy associated with autoimmune thyroiditis

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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