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Any systemic lupus erythematosus in which the cause of the disease is a variation in the PLD4 gene.
PLD4 function has not been fully characterized.
Systemic lupus erythematosus 18 has been associated with mutations in the PLD4 gene on chromosome 14.
Genetic testing for PLD4 is available. Testing is considered supportive for diagnosis.
Biomarker and diagnostic research for systemic lupus erythematosus 18 has been reported in the published literature.
No clinical trials have been registered for systemic lupus erythematosus 18.
228 publications have been identified in PubMed for systemic lupus erythematosus 18. Research spans Epidemiology / Natural History (39%), Review / Meta-Analysis (18%), and Clinical Trial Publication (16%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 90 | 39% |
Data assembled from 5 of 12 sources · Last updated Sep 18, 2026, 3:44 AM UTC
Online Mendelian Inheritance in Man
Research summaries
42 |
18% |
Clinical study results | 37 | 16% |
Laboratory research | 23 | 10% |
Testing and diagnosis research | 18 | 8% |
Patient case studies | 11 | 5% |
New treatment approaches | 4 | 2% |
Other research | 3 | 1% |
Tayer-Shifman OE (2026). [PMID: 41102434](https://pubmed.ncbi.nlm.nih.gov/41102434/). *Int Urol Nephrol*. [Clinical Trial Publication]
Yu Z (2026). [PMID: 41570871](https://pubmed.ncbi.nlm.nih.gov/41570871/). *Autoimmun Rev*. [Review / Meta-Analysis]
Liu D (2026). [PMID: 42168466](https://pubmed.ncbi.nlm.nih.gov/42168466/). *Eur J Clin Pharmacol*. [Review / Meta-Analysis]
Shin JM (2026). [PMID: 41496726](https://pubmed.ncbi.nlm.nih.gov/41496726/). *Lupus*. [Epidemiology / Natural History]
Yang J (2026). [PMID: 41132137](https://pubmed.ncbi.nlm.nih.gov/41132137/). *Arthritis Care Res (Hoboken)*. [Epidemiology / Natural History]
Classen P (2026). [PMID: 41004309](https://pubmed.ncbi.nlm.nih.gov/41004309/). *Clin Exp Rheumatol*. [Epidemiology / Natural History]
Chen Y (2026). [PMID: 40626618](https://pubmed.ncbi.nlm.nih.gov/40626618/). *J Clin Nurs*. [Epidemiology / Natural History]
Tani C (2026). [PMID: 41655581](https://pubmed.ncbi.nlm.nih.gov/41655581/). *Lancet Rheumatol*. [Epidemiology / Natural History]
Ye M (2026). [PMID: 42233611](https://pubmed.ncbi.nlm.nih.gov/42233611/). *Ann Med*. [Clinical Trial Publication]
Blagov A (2026). [PMID: 41914176](https://pubmed.ncbi.nlm.nih.gov/41914176/). *Front Biosci (Schol Ed)*. [Review / Meta-Analysis]