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Type 1 temperature sensitive oculocutaneous albinism (OCA1-TS) is an extremely rare form of OCA1 characterized by the production of temperature sensitive tyrosinase proteins leading to dark hair on the legs, arms and chest (cooler body areas) and white hair on the scalp, axilla and pubic area (warmer body areas).
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for temperature-sensitive oculocutaneous albinism type 1.
2 publications have been identified in PubMed for temperature-sensitive oculocutaneous albinism type 1. Research spans Case Report / Case Series (100%).
Luo L (2025). [PMID: 40313672](https://pubmed.ncbi.nlm.nih.gov/40313672/). *Front Pediatr*. [Case Report / Case Series]
Bjeloš M (2024). [PMID: 38928147](https://pubmed.ncbi.nlm.nih.gov/38928147/). *Int J Mol Sci*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:45 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center