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A thymic epithelial neoplasm characterized by the presence of expanded areas which resemble the normal thymic cortex. The neoplastic epithelial cells are small and scant and there is a dense T-lymphocytic component present. Areas of medullary differentiation with or without Hassall's corpuscles are also present. It may be associated with myasthenia gravis, pure red cell aplasia, and hypogammaglobulinemia. It has a low grade malignant potential. The majority of cases occur in the anterior mediastinum as Masaoka stage I tumors. A minority of the cases occur as stage II tumors.
Biomarker and diagnostic research for thymoma type B1 has been reported in the published literature.
No clinical trials have been registered for thymoma type B1.
6 publications have been identified in PubMed for thymoma type B1. Research spans Diagnostic / Biomarker (17%), Review / Meta-Analysis (17%), and Case Report / Case Series (17%).
Fujikura K (2026). [PMID: 41344988](https://pubmed.ncbi.nlm.nih.gov/41344988/). *The Journal of pathology*. [Basic Science / Preclinical]
Suster DI (2025). [PMID: 40666531](https://pubmed.ncbi.nlm.nih.gov/40666531/). *Mediastinum (Hong Kong, China)*. [Review / Meta-Analysis]
Yu XT (2025). [PMID: 40328968](https://pubmed.ncbi.nlm.nih.gov/40328968/). *Genes and immunity*. [Gene Therapy / Novel Therapeutics]
Yin Y (2024). [PMID: 39533067](https://pubmed.ncbi.nlm.nih.gov/39533067/). *Scientific reports*. [Epidemiology / Natural History]
Kurokawa K (2024). [PMID: 39034967](https://pubmed.ncbi.nlm.nih.gov/39034967/). *JTO clinical and research reports*. [Case Report / Case Series]
Data assembled from 2 of 12 sources · Last updated Sep 18, 2026, 8:54 AM UTC