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A squamous cell carcinoma that arises from the mucosal lining of the tonsil and tends to metastasize early to the lymph nodes. It predominantly affects middle aged and elderly patients who have a history of alcohol and tobacco use. Patients may present with tonsillar swelling, sore throat, pain radiating to the ipsilateral ear, or a neck mass.
Biomarker and diagnostic research for tonsillar squamous cell carcinoma has been reported in the published literature.
2 clinical trials registered, 1 recruiting. Interventions under study include procedural interventions. Pipeline includes 1 PHASE2, 1 NA. Research is primarily sponsored by academic and government institutions.
40 publications have been identified in PubMed for tonsillar squamous cell carcinoma. Research spans Case Report / Case Series (45%), Review / Meta-Analysis (15%), and Diagnostic / Biomarker (13%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 18 |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 8:28 AM UTC
Research summaries | 6 | 15% |
Testing and diagnosis research | 5 | 13% |
Laboratory research | 4 | 10% |
Clinical study results | 3 | 8% |
Disease patterns and progression | 3 | 8% |
Other research | 1 | 3% |
Näsman T (2026). [PMID: 41129372](https://pubmed.ncbi.nlm.nih.gov/41129372/). *Int J Cancer*. [Review / Meta-Analysis]
Bahsoun A (2026). [PMID: 42156098](https://pubmed.ncbi.nlm.nih.gov/42156098/). *BMJ Case Rep*. [Case Report / Case Series]
Oh B (2026). [PMID: 41809313](https://pubmed.ncbi.nlm.nih.gov/41809313/). *Cureus*. [Case Report / Case Series]
Harris MK (2026). [PMID: 41926109](https://pubmed.ncbi.nlm.nih.gov/41926109/). *JAMA Otolaryngol Head Neck Surg*. [Diagnostic / Biomarker]
Huang W (2026). [PMID: 42180096](https://pubmed.ncbi.nlm.nih.gov/42180096/). *Front Oncol*. [Case Report / Case Series]
Li X (2025). [PMID: 40109336](https://pubmed.ncbi.nlm.nih.gov/40109336/). *Front Immunol*. [Case Report / Case Series]
Abana CO (2025). [PMID: 41288848](https://pubmed.ncbi.nlm.nih.gov/41288848/). *Discov Oncol*. [Epidemiology / Natural History]
Yu D (2025). [PMID: 40959104](https://pubmed.ncbi.nlm.nih.gov/40959104/). *J Cancer*. [Diagnostic / Biomarker]
Peterson AM (2025). [PMID: 40810933](https://pubmed.ncbi.nlm.nih.gov/40810933/). *JAMA Otolaryngol Head Neck Surg*. [Review / Meta-Analysis]
Fan R (2025). [PMID: 40578983](https://pubmed.ncbi.nlm.nih.gov/40578983/). *In Vivo*. [Case Report / Case Series]