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A squamous cell carcinoma that involves the oropharynx.
Biomarker and diagnostic research for oropharynx squamous cell carcinoma has been reported in the published literature.
118 clinical trials registered, 43 recruiting. Interventions under study include procedural interventions, drug therapy, other interventions, and biologic therapy. Pipeline includes 7 PHASE3, 58 PHASE2, 19 PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT07195734](https://clinicaltrials.gov/study/NCT07195734) |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 1:07 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer |
PHASE2 |
National Cancer Institute (NCI) |
RECRUITING |
[NCT06088381](https://clinicaltrials.gov/study/NCT06088381) | Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) | PHASE2 | University of Maryland, Baltimore | RECRUITING |
[NCT06980038](https://clinicaltrials.gov/study/NCT06980038) | Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer | PHASE2 | National Cancer Institute (NCI) | RECRUITING |
[NCT05918510](https://clinicaltrials.gov/study/NCT05918510) | Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus | — | Regina Elena Cancer Institute | RECRUITING |
[NCT07172256](https://clinicaltrials.gov/study/NCT07172256) | CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs | PHASE2 | Yale University | RECRUITING |
11 publications have been identified in PubMed for oropharynx squamous cell carcinoma. Research spans Diagnostic / Biomarker (55%), Epidemiology / Natural History (27%), and Clinical Trial Publication (9%).
Research Type | Count | % of Total |
|---|---|---|
Testing and diagnosis research | 6 | 55% |
Disease patterns and progression | 3 | 27% |
Clinical study results | 1 | 9% |
Laboratory research | 1 | 9% |
Gao L (2026). [PMID: 42141526](https://pubmed.ncbi.nlm.nih.gov/42141526/). *J Med Imaging Radiat Oncol*. [Clinical Trial Publication]
Hennocq Q (2026). [PMID: 41654300](https://pubmed.ncbi.nlm.nih.gov/41654300/). *Journal of stomatology, oral and maxillofacial surgery*. [Diagnostic / Biomarker]
Teich T (2026). [PMID: 41064927](https://pubmed.ncbi.nlm.nih.gov/41064927/). *Histopathology*. [Diagnostic / Biomarker]
Campo F (2026). [PMID: 41735552](https://pubmed.ncbi.nlm.nih.gov/41735552/). *European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery*. [Diagnostic / Biomarker]
Bakhtiar M (2026). [PMID: 42061149](https://pubmed.ncbi.nlm.nih.gov/42061149/). *Oral Oncol*. [Diagnostic / Biomarker]
Smee R (2025). [PMID: 40160176](https://pubmed.ncbi.nlm.nih.gov/40160176/). *The Journal of laryngology and otology*. [Epidemiology / Natural History]
Lenoci D (2025). [PMID: 39941896](https://pubmed.ncbi.nlm.nih.gov/39941896/). *Cancers*. [Basic Science / Preclinical]
Bakhtiar M (2025). [PMID: 40322795](https://pubmed.ncbi.nlm.nih.gov/40322795/). *Head & neck*. [Diagnostic / Biomarker]
Martínez-Ramírez J (2025). [PMID: 41450111](https://pubmed.ncbi.nlm.nih.gov/41450111/). *Oral diseases*. [Epidemiology / Natural History]
Hong SA (2024). [PMID: 38511301](https://pubmed.ncbi.nlm.nih.gov/38511301/). *Head & neck*. [Epidemiology / Natural History]