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trigeminal trophic syndrome (TTS) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

trigeminal trophic syndrome

MONDO:0800478

Also known as:TTS

Overview

A syndrome characterized by an uncommon and relatively unknown cause of facial ulceration that occurs after damage to the trigeminal nerve. It characteristically involves non-healing facial ulceration(s) with accompanying anesthesia, paresthesia, and dysesthesia along the distribution of a trigeminal dermatome.

Diagnosis

Biomarker and diagnostic research for trigeminal trophic syndrome has been reported in the published literature.

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for trigeminal trophic syndrome.

25 publications have been identified in PubMed for trigeminal trophic syndrome. Research spans Case Report / Case Series (68%), Other (12%), and Diagnostic / Biomarker (8%).

Research Type	Count	% of Total
Patient case studies	17	68%

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:45 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:664901

Questions for Your Care Team

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trigeminal trophic syndrome

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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