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A bacterial infectious disorder contracted by consumption of food or drink contaminated with Salmonella typhi. This disorder is common in developing countries and can be treated with antibiotics.
Biomarker and diagnostic research for typhoid fever has been reported in the published literature.
1 FDA-approved treatment is available for typhoid fever, including CIPROFLOXACIN (CIPRO, approved 1997).
Brand Name | Generic Name | Mechanism | Approved | Market Status |
|---|---|---|---|---|
Estimated prevalence: Unknown (Unknown prevalence).
10 clinical trials registered, 2 recruiting. Interventions under study include drug therapy, biologic therapy, and other interventions. Pipeline includes 3 PHASE4, 2 PHASE3, 1 EARLY_PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT03705585](https://clinicaltrials.gov/study/NCT03705585) |
Data assembled from 5 of 12 sources · Last updated Sep 18, 2026, 6:09 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
CIPROFLOXACIN |
— |
1997 |
Available |
Gene therapy approaches for typhoid fever have been reported in the published literature.
10 trials found
CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera |
PHASE4 |
University of Maryland, Baltimore |
RECRUITING |
[NCT04878549](https://clinicaltrials.gov/study/NCT04878549) | Transcriptomic Responses for the Identification of Pathogens | — | University of Sheffield | RECRUITING |
319 publications have been identified in PubMed for typhoid fever. Kisho has analyzed 144 by research type. Research spans Epidemiology / Natural History (35%), Basic Science / Preclinical (19%), and Review / Meta-Analysis (17%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 50 | 35% |
Laboratory research | 28 | 19% |
Research summaries | 25 | 17% |
Clinical study results | 16 | 11% |
Patient case studies | 13 | 9% |
Testing and diagnosis research | 9 | 6% |
New treatment approaches | 3 | 2% |
Chen Y (2026). [PMID: 40436138](https://pubmed.ncbi.nlm.nih.gov/40436138/). *J Adv Res*. [Review / Meta-Analysis]
Di Benedetto R (2026). [PMID: 42099609](https://pubmed.ncbi.nlm.nih.gov/42099609/). *Front Immunol*. [Basic Science / Preclinical]
Murthy S (2026). [PMID: 41240962](https://pubmed.ncbi.nlm.nih.gov/41240962/). *The Lancet. Infectious diseases*. [Review / Meta-Analysis]
Mogasale VV (2026). [PMID: 41908250](https://pubmed.ncbi.nlm.nih.gov/41908250/). *Lancet Reg Health Southeast Asia*. [Epidemiology / Natural History]
Monica LI (2026). [PMID: 41837092](https://pubmed.ncbi.nlm.nih.gov/41837092/). *International journal of surgery case reports*. [Case Report / Case Series]
Galán JE (2026). [PMID: 42041253](https://pubmed.ncbi.nlm.nih.gov/42041253/). *Microbiol Mol Biol Rev*. [Review / Meta-Analysis]
Mogasale VV (2026). [PMID: 41551375](https://pubmed.ncbi.nlm.nih.gov/41551375/). *The Lancet regional health. Southeast Asia*. [Review / Meta-Analysis]
Bai Y (2026). [PMID: 40393644](https://pubmed.ncbi.nlm.nih.gov/40393644/). *Journal of advanced research*. [Basic Science / Preclinical]
Kotsias-Konopelska S (2026). [PMID: 41562595](https://pubmed.ncbi.nlm.nih.gov/41562595/). *Dtsch Arztebl Int*. [Review / Meta-Analysis]
Ibarz Pavon AB (2025). [PMID: 40964609](https://pubmed.ncbi.nlm.nih.gov/40964609/). *Gates open research*. [Epidemiology / Natural History]