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Any vesicoureteral reflux in which the cause of the disease is a mutation in the ROBO2 gene.
Features include: Vesicoureteral reflux and Renal hypoplasia.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Kidneys and urinary system | 1 | Renal hypoplasia |
ROBO2 function has not been fully characterized.
Vesicoureteral reflux 2 is associated with mutations in the ROBO2 gene on chromosome 3.
Genetic testing for ROBO2 is available. Testing is considered confirmatory for diagnosis.
Biomarker and diagnostic research for vesicoureteral reflux 2 has been reported in the published literature.
No clinical trials have been registered for vesicoureteral reflux 2.
21 publications have been identified in PubMed for vesicoureteral reflux 2. Research spans Clinical Trial Publication (29%), Basic Science / Preclinical (24%), and Epidemiology / Natural History (24%).
Research Type | Count | % of Total |
|---|---|---|
Clinical study results | 6 | 29% |
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 12:51 AM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
5 |
24% |
Disease patterns and progression | 5 | 24% |
Research summaries | 3 | 14% |
Testing and diagnosis research | 2 | 10% |
Yu M (2026). [PMID: 41977230](https://pubmed.ncbi.nlm.nih.gov/41977230/). *Int J Mol Sci*. [Basic Science / Preclinical]
Kumar S (2026). [PMID: 41576029](https://pubmed.ncbi.nlm.nih.gov/41576029/). *PLoS genetics*. [Basic Science / Preclinical]
Kim JK (2026). [PMID: 42190252](https://pubmed.ncbi.nlm.nih.gov/42190252/). *J Urol*. [Review / Meta-Analysis]
Amedzrovi Agbesi RJ (2026). [PMID: 39651614](https://pubmed.ncbi.nlm.nih.gov/39651614/). *Neurogastroenterology and motility*. [Clinical Trial Publication]
Tobia-Gonzalez S (2026). [PMID: 42097120](https://pubmed.ncbi.nlm.nih.gov/42097120/). *J Pediatr Urol*. [Epidemiology / Natural History]
Yoon HS (2026). [PMID: 40696791](https://pubmed.ncbi.nlm.nih.gov/40696791/). *Movement disorders clinical practice*. [Clinical Trial Publication]
Pogorelić Z (2026). [PMID: 41892814](https://pubmed.ncbi.nlm.nih.gov/41892814/). *Medical sciences (Basel, Switzerland)*. [Clinical Trial Publication]
Abdulrasak M (2025). [PMID: 40428879](https://pubmed.ncbi.nlm.nih.gov/40428879/). *Medicina (Kaunas, Lithuania)*. [Review / Meta-Analysis]
Mohan Kunnath S (2025). [PMID: 40108801](https://pubmed.ncbi.nlm.nih.gov/40108801/). *Neurourology and urodynamics*. [Clinical Trial Publication]
Xu TO (2025). [PMID: 40032536](https://pubmed.ncbi.nlm.nih.gov/40032536/). *Journal of pediatric surgery*. [Epidemiology / Natural History]