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Type 2A von Willebrand disease (type 2A VWD) is a subtype of type 2 VWD characterized by a bleeding disorder associated with a decrease in the affinity of the Willebrand factor (von Willebrand factor; VWF) for platelets and the subendothelium caused by a deficiency of high molecular weight VWF multimers.
Estimated prevalence: Unknown (Unknown prevalence).
1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily industry-sponsored.
6 publications have been identified in PubMed for von Willebrand disease type 2A. Research spans Case Report / Case Series (33%), Other (17%), and Review / Meta-Analysis (17%).
Seidizadeh O (2026). [PMID: 41509548](https://pubmed.ncbi.nlm.nih.gov/41509548/). *Res Pract Thromb Haemost*. [Other]
Seidizadeh O (2026). [PMID: 41453393](https://pubmed.ncbi.nlm.nih.gov/41453393/). *Semin Thromb Hemost*. [Review / Meta-Analysis]
Valenti GG (2026). [PMID: 41968449](https://pubmed.ncbi.nlm.nih.gov/41968449/). *Haemophilia*. [Case Report / Case Series]
Wang LJ (2025). [PMID: 40298995](https://pubmed.ncbi.nlm.nih.gov/40298995/). *Ann Hematol*. [Case Report / Case Series]
Zhang Z (2025). [PMID: 40958414](https://pubmed.ncbi.nlm.nih.gov/40958414/). *Mol Ther*. [Gene Therapy / Novel Therapeutics]
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 11:56 AM UTC
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Genetic and Rare Diseases Info Center
AI-curated news mentioning von Willebrand disease type 2A
Updated Apr 12, 2026
A recent study published in PubMed highlights a rare case of mucosal bleeding in a newborn, revealing an unusual combination of Type 2A and Type 2N von Willebrand Disease. This research contributes to the understanding of bleeding disorders in neonates.